Myogenic Tubisimiao Decoction In The Treatment Of Heat Accumulation Type Gouty Arthritis Clinical Study

Gout is a purine metabolic disorders and excretion caused byabnormal hyperuricemia.It has reversible rate crystal abnormaldeposition of heterogeneous disease and belongs to a kind ofarthritis. The clinical features of acute gouty arthritis havemany types.Such as chronic arthritis and jointdeformities,chronic interstitial ect. Often involving thekidneys caused by chronic interstitial nephritis, and uric acidkidney stone formation. Closely related to the incidence ofthis disease and people’s daily lives, especially dietaryfactors play a crucial role in the pathogenesis of gout. Withthe rapid development of China’s economy in recent years, theincidence rate showed an increasing trend, and tend to beyounger age of onset, as one of them presents its incidenceincreased year after year, and becoming younger age of onset.Gout cause the joint pain unbearable,Gout on the one handcause severe joint pain, and even joint deformity, causing painto the patient experience; On the other hand, a variety ofclinical risk factors for common diseases, the present study ismore popular gout and cardiovascular and diseases, such as goutand coronary heart disease, gout and stroke. Become great harmnot only people’s health but also the quality of life. ObjectiveWe observe and record the information about the TubisimiaoDecoction in the treatment of Heat Accumulation type Goutyarthritis. The study including clinical curative effect, safetyof the treatment, the short term rate of recur. Through thismentor we can judge the Chinese medicine named TubisimiaoDecoction. And it also shows more evidences about the Chinesemedicine uses for clinic.MethodsCollection gouty arthritis patients with a total of60cases,which is coming from the Frist hospital of Wuhanincluding specialist clinics, endocrine and rheumatologypatients hospitalized. In accordance with the principle ofrandomization, were included in two groups. One of them calledthe treatment group, the other named control group. Thepatients who are belonged to Control group take colchicinetablets and capsules celecoxib. The other group plus TubisimiaoDecoction for the treatment. Month for a course of treatment.We Record changes of clinical symptom improvement, decreasedblood levels of uric acid in order to assess its therapeuticeffect.At the same time, we collect the blood tests before andafter treatment targets to observe the safety. Finally,followed up for6months to observe the recurrence of thesituation,so we can understand the short-term prognosis.Thedata collected in this study are analyzed using SPSS18.0software, process.Some of the measurement data with mean±standard deviation format. Comparison of data between groupsusing t-test. Level data are compared by rank sum test. ResultsThe results shows that the treatment group in relievingarthritis symptoms, improve clinical symptoms more obvious thanin the control group (P <0.05). TCM syndrome score before andafter treatment aspects of the treatment group improved evenbetter than the control group (P <0.05). Symptomatic efficacyof the treatment group better than the control group (P <0.05).But the two groups in lower blood uric acid levels are notsignificantly different (P>0.05). Comprehensive assessment ofefficacy in the treatment group and the control groupconsiderable effect (P>0.05). Compared to the control group,patients in the treatment group during follow-up, relapsefrequency was significantly lower (P <0.05). Before and aftertreatment, routine blood test indicators, such as kidney, liverfunction did not change significantly, suggesting thatTubisimiao Decoction can be used for clinic safely.ConclusionsTreatment of gouty arthritis in the standard western medicine,based on the increase in Tubisimiao Decoction often than simplyusing western medicine better.The method can collaborate withWestern medicine, rapid improvement in arthritis, smooth,slowly lower uric acid levels, reducing recurrent gout andother aspects have a positive effect. And during the wholetreatment we are not observed in patients with discomfort andcan not be tolerated, the clinical use of good safety. Used inthe treatment of gout for parties to provide practical andobjective evidence.