Clinical Study On Gouty Arthritis Treated With Eliminating Turbid, Resolving Blood Stasis, Regulating And Reinforcing Spleen And Kidney Following Traditional Chinese Medicine

目的:观察泄浊化瘀调益脾肾法治疗痛风性关节炎的临床疗效,探讨其作用机理。方法:将56例患者随机分为两组,治疗组32例用泄浊化瘀调益脾肾法基本方(由土茯苓,萆薢,何首乌,苍术,泽兰,泽泻,全当归,桃仁,红花,川牛膝等10多种组成)加减治疗,对照组24例用秋水仙碱,别嘌呤醇常规治疗,进行用药前两组患者血沉,血尿酸,肌苷,尿素氮,主要临床症状,舌苔脉象,综合疗效,不良反应等方面的临床观察。结果:总有效率治疗组87．5%,对照组75%,治疗组优于对照组,两组比较有统计学意义(P<0．05)。结论:泄浊化瘀调益脾肾法为治疗痛风提供了一种安全有效的方法和途径。Clinical study on gouty arthritis treated with eliminating turbid, resolving blood stasis, regulating and reinforcing spleen and kidney followingtraditional Chinese medicineABSTRACTObject: The efficacy on gouty arthritis treated with eliminating turbid, resolving blood stasis, regulating and reinforcing spleen and kidney following traditional Chinese medicine was evaluated, and the primary mechanism on how the herbal therapy was explored.Methods: 56 cases with gouty arthritis were randomized into two groups. The patients in treated group (32 cases) was administered with the herbal medicine following eliminating turbid, resolving blood stasis, regulating and reinforcing spleen and kidney following traditional Chinese medicine, and the basic prescription included glabrous greenbrier rhizome, radix polygoni muliflori, eupatorium, water plantain tuber, angelica root, peach seed, flos carthami, cyathulae. The patients in control group (24 cases) were treated with routine therapy in Western medicine, including Colchicina and Allopurinol. The erythrosedimentation, blood uric acid, carnine, urea nitrogen, major symptoms, tongue appearance and pulse feeling were tested before and after the treatment. The comprehensive effect and adverse effect were evaluated in the study. Results: The 87．5% effective rate was obtained in the patients of treated group, and 75% effective rate in control group. The difference between two groups was significant (P<0．05) .Conclusion: The herbal medicine with eliminating turbid, resolving blood stasis, regulating and reinforcing spleen and kidney following traditional Chinese medicine could be a safe, effective way to treat gouty arthritis.