Clinical Analysis Of122Cases Of Test-tube Prematurity On Early Complications And Therapeutic Effect

Objective：To study early complications of122cases of test-tubeprematurity，observe therapeutic effect during hospitalization，evaluatetheir early survival ability，and provide theory reference for the choicesof assisted reproductive technique.Methods： Retrospective analysis was conducted in the clinical data of122test-tube prematurity and183nature prematurity that treated in ourhospital from January in2009to Octobor in2012，including maternalcomplications, birth condition，early complications and therapeuticeffect. The rank sum test and T-test was used to compare the continuousvariables in skewed distribution and ordered categorical variable the chisquare test was used to compare disordered categorical variables.Results：There was no statistically significant difference between the twogroup in maternal complications （P﹥0.05）, pregnancy inducedhypertension, premature rupture of membrane, placental abruption,placenta praevia, gestational diabetes and cytomegalovirus infection. Inthe comparison of early complications， incidence of RDS wasstatistically higher in the test-tube prematurity group(25.4%) than in thecontrol group(12.0%)（P﹤0.05），in the other early complications oftest-tube group, the incidence rate of neonatal anemia(46.7%)was thehighest than other complications，in descending orde:PDA(28.7%),neonatal sepsis(18.0%), unconjugated hyperbilirubinemia ofnewborn(13.1%),IVH(9.8%),ROP(6.6%), pulmonary hemorrhage(4.1%), NEC(0.8%)；meanwhile, the incidence rate of neonatal anemia in thecontrol group was50.3%, in descending orde:PDA (31.7%),neonatalsepsis(19.7%),unconjugated hyperbilirubinemia ofnewborn(16.9%),ROP(9.3%),IVH(8.7%),pulmonary hemorrhage(4.4%),NEC(2.2%)，there was no statistically significant difference in thoseearly complication（sP﹥0.05）.There were four cases of malformation inthe test-tube group，including cleft lip，hypospadias，choroidal and iriscolobama，dubious chromosomal disorder，and no malformation in thethe control group，incidences of malformation was statistically higher inthe test-tube group(P﹤0.05）.Mortility was statistically higher in thetest-tube group(9.0%)(P﹤0.05）.Conclusion：Test-tube prematurity are more likely to suffer fromRDS;there are higher rates of conginatal malformation in test-tubeprematurity,we should choose assisted reproductive technology morecarefully and enhance gene diagnosis of hereditary disease;there arehigher rates of mortility in test-tube prematurity,even earlymortility;there are worse ability of test-tube prematurity,we shoulddiognosis more cautiously and take more monitoring and hygiene.