| Objective:To explore and discuss the improvement effect of Niaoshitong Pill on patients’common complications during double J tube indwelling, which provides new methods and ideas for the clinical treatment to related complications during double J tube indwelling.Method:In this clinical study, the subjects were those who suffer from ureteral calculus and hospitalize in urological surgery department of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from October 2013 to March 2015. All patients conform to the inclusion and exclusion criteria, and are divided into two groups randomly, treatment group 31 cases and control group 28 cases, respectively. During hospitalization, the unilateral URSL operation is conducted to two groups while the length of double J tubes depends on patient’s height, and these double J tubes are 4.7F polyurethane ureteral stents produced by Bard. After operation, two group patients were given a routine anti-infection, analgesia, hemostasis and other treatment. The second day after surgery, all the patients are adopted a semi-liquid diet, such as patients who suffer from severe waist pain can be treated with tramadol hydrochloride injection medication or other medications for symptomatic treatment.2 to 3 days after completed operation, then review KUB to observe the position exception of indwelling double J tube. If the position of patient’s double J tube is normal and urine comes from urethral tube is pellucid, then remove the urethral tube in 3 to 4 days after surgery and continue to be hospitalized for one-day observation, if without any special discomfort, patients can be discharged. After discharge, two groups patients are taken with levofloxacin tablets for one week. In addition, treatment group was given with service Niaoshitong pill (Guangdong Dongguan Asia Pharmaceutical Co., Ltd. production), patient of the enjoin on the 8th day after discharge began taking daily 1 bag bid until back extraction of double J tube. The control group is same as treatment group except taking Niaoshitong pill. In addition, Both groups are required to drink more water (daily water intake kept 2500ml～3000ml), and cannot walk for a long line, nor participate in violent activities. Both groups are required to remain double J tube for six weeks (which can fluctuate around 3 to 4 days), then removes them when back to hospital. According to symptoms questionnaire related to patients’self-designed double J tube while back to hospital, investigate the therapeutic effect of the two groups, respectively. Then handle the results with SPSS17.0 statistical software, all measurement data is represented with mean±standard deviation (X±S), and the measurement data which conforms to the normal distribution are adopted two independent sample t tests, on the contrary, takes Wilcoxon rank and inspection as methods for those which doesn’t conform to normal distribution, and efficiently adopts chi-square test. P<0.05 was considered to be statistical significance.Result:After six weeks,28 cases have completed the trial in treatment group while 26 cases in control group. In terms of three urination symptoms, i. e., inadequacy urination, urgent urination and hematuria occurrence time, these investigation projects’score difference was Wilcoxon ranked and tested, P values were 0.028,0.017 and 0.028, respectively. P values are all less than 0.05 so that the difference has a statistical significance, which indicates that Niaoshitong pill treatment group is prior to the control group. And an investigation score difference about one more urination within two hours between two groups is statistically analyzed, as a result, P value is 0.352, which is more than 0.05 so that the difference has no statistical significance, indicating that the treatment effect on one more urination within two hours between two groups has no significant difference. In terms of back pain, curative scores difference between two groups are Wilcoxon ranked and tested, as a result, the P value equals to 0.031, which is less than 0.05 so that it has a statistical significance. The life quality score difference between two groups is statistically analyzed, as a result, P value equals to 0.012, which is less than 0.05 so that it has statistical significance. The above two items indicates that the treatment group has certain advantages compared with control group in the aspects of relieving patients’lower back pain and improving quality of life. In terms of adverse reaction, no specific adverse reaction comes out both two groups.Conlusions:Niaoshitong pill can improve patients’double J tube-related complication after URSL operation, and also have significant effect especially on relieving patients’bladder irritation, hematuria, back pain and other symptoms, as well as have no significant adverse reactions. |
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