| Objective:A comparative analysis of perinatal maternal and child complications was performed by retrospectively collecting single-born test-tube babies with different infertility factors in order to explore whether there were differences in maternal and child complications under infertility factors.It is hoped that the result will provide theoretical basis for obstetric medical workers about health care and birth inspection during pregnancy.Methods:Through the hospital's medical record browser,the author retrospectively collected single-born test-tube babies that were hospitalized in three maternity wards in Affiliated hospital of yan 'an university from January 2013 to January 2019.According to the inclusion and exclusion criteria,377 subjects who met the criteria were divided into 4 groups according to the infertility factors,namely the fallopian tube factor group,the ovulation disorder group,the male factor group and unexplained groups.Detailed information was recorded on the age,body mass index,gestational weeks,and mode of production of pregnant mothers,as well as maternal gestational complications such as hypertensive disorder of pregnancy(excluding chronic hypertension with superimposed preeclampsia and chronic hypertension),preterm birth and gestational diabetes mellitus(GDM);abnormalities of some fetal appendages;neonatal gender,birth weight,gestational week and some fetal abnormalities.The data was analyzed by SPSS 22.0 statistical software.There were differences between the four groups,and the comparison was performed between the two groups.Results:1.Comparison of the number of test-tube babies in different reasons: This study included 377 test-tube babies with complete medical records.The fallopian tube factorgroup was 198,accounting for 52.52%;the ovulation disorder group was 85,accounting for 22.55%;the male factor group was 50,accounting for 13.26%;the unexplained group was 44,accounting for 11.67%.As Figure 1.2.Comparison of age and body mass index in four groups of parturients: There was no statistical difference in age between the four groups(P=0.124).However,there was a statistically significant difference in body mass index(P = 0.000).The ovulation disorder group had the highest body mass index of(30.48±5.62)kg/m2.The Bonferroni method was used to compare the comparison between the two groups.The ovulation disorder group was compared with the other three groups(both P<0.05).There were statistically significant.As Table 1.3.Comparison of gestational weeks and weight of newborn infants in four groups:There was no statistical difference among the four groups in the gestational weeks of birth and the weight of the newborn.As Table 2.4.Comparison of pregnancy complications and incidence of gestational diabetes mellitus in four groups: There were 30 cases of hypertensive disorder of pregnancy in the ovulatory disorder group and the incidence rate was 35.29%,which was the highest among the four groups.There was a statistical difference between the four groups with comparing P=0.000.There was a statistically significant difference between the ovulation disorder group and the fallopian tube factor group(P=0.000)after the test level was adjusted to 0.008,while there was no statistical difference between the other groups.The incidence of GDM in the ovulatory disorder group was 14.12%,which was the highest among the four groups.There was a statistically significant difference between the four groups(P=0.014).Further two-to-two comparison,there was a statistically significant difference between the tubal factors and the ovulation disorder group(P=0.002),and there was no statistical difference between the other groups.The incidence of preterm birth in the ovulatory disorder group was 21.18%,which was the highest among the four groups.There was a statistically significant difference between the four groups(P=0.017).Further comparison between the two groups showed that the premature birth in the ovulation disorder group was much higher than that in the fallopian tube group,and there was a statistical difference(P=0.001).There were no statistical differences between the remaining groups.As Figure 2 and Table 3.5.Comparison of abnormal fetal incidence among four groups: The incidence of birth defects in the ovulation disorder group and the male factor group were 7.06% and6.00% respectively,which were higher than the other two groups,and the four groups were statistically significant(P=0.048).However,there was no statistical significance between the groups after correction.There were no statistical differences between the four groups in low birth weight infants,macrosomia and fetal distress.As Table 4.6.Comparison of abnormal incidence rates of four groups of fetal appendages:There was no statistically significant difference between the four groups in premature rupture of membranes,oligohydramnios and placenta previa.As Table 5.7.Comparison of four groups in neonatal gender and maternal production methods:There was no statistically significant difference in the proportion of male,female,and cesarean section between the four groups.Conclusion:1.The body mass index of the ovulation disorder group was higher than that of the fallopian tube,male and unexplained group,and there were statistical significance compared with other three groups.2.The incidence of ovulatory disorder group was the highest in the four groups in hypertensive disorder of pregnancy,gestational diabetes mellitus and preterm birth,and there were statistically significant compared with the fallopian tube factor group.3.The incidence of birth defects in neonates with ovulation disorders and male factors is higher than that of fallopian tubes and unexplained groups.There may be differences between the four groups. |
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