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Clinical Research Of Jiaweilizhong Soup Intervenes The Spleen And Kidney Yang Deficiency Type Of Colorectal Cancer After Chemotherapy

Posted on:2013-07-17Degree:MasterType:Thesis
Country:ChinaCandidate:B C ChenFull Text:PDF
GTID:2234330395466412Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
Object:1.To observe the symptoms after the intervention of the Jiaweilizhong intervenes spleen and kidney Yang deficiency colorectal cancer after the chemotherapy.2.To assess the efficacy and safety of the Jiaweilizhong in the treatment of colorectal cancer chemotherapy spleen and kidney Yang deficiency.3.For clinical treatment of colorectal cancer chemotherapy after tumor disease related to provide reference.Methods:1.The68patients with colorectal cancer chemotherapy patients meet eligibility criteria of were randomly divided into two groups, the control group of33cases, the treatment group35examples; The control group to chemotherapy for the reaction and toxicity of the support symptomatic treatment, the treatment group support in symptomatic treatment based on oral Jiaweilizhong.2.Both groups are observed21days. The treatment group giving the soup for2times a day, every time150ml.3.Observe two groups of cases before treatment, the7th day after treatment, the14th day,21th day after treatment of traditional Chinese medicine clinical symptoms total credit and main points of the syndrome, Kps scores improve changes, tumor marker CEA, CA-199changes, immunology CD3, CD4, CD8, CD4/CD8changesResults:1.After statistical analysis,compare the treatment group Chinese clinical symptoms total credit before treatment and after has significant difference (P<0.01), comparisons among the groups the treatment group and control group in Chinese clinical symptoms after has difference (P<0.05), all have statistical significance.2.The quality of life of the patients (KPS score) by statistical analysis, the treatment group therapy can improve stability and KPS after scoring level,compare the treatment group and control group KPS score is statistically significant (P<0.01).3. On tumor markers, CEA CA19-9, statistical analysis, the treatment group before and after treatment within the group doesn’t has statistically significant (P>0.05), treatment after comparison between the two groups doesn’t has statistically significant (P>0.05).4. On the immune index CD3, CD4, CD8, CD4/CD8changes between the two groups are compared and the treatment group compared before and after treatment has statistically significant (P<0.05).5. Adverse reaction:two groups of patients before and after the treatment of treatment routine blood, kidney and liver function, electrocardiogram, etc no change.Conclusion:Jiaweilizhong treat the colorectal cancer after chemotherapy classify to the spleen and kidney Yang deficiency has obvious curative effect, it could improves the clinical symptoms in patients with traditional Chinese medicine, and improve the quality of life and immunity, but for the improvement of tumor marker doesn’t has statistical significance, the treatment is safe and effective, no obvious adverse reaction.
Keywords/Search Tags:Jiaweilizhong soup, Colorectal cancer, Spleen and kidney Yang syndrome, Clinical research
PDF Full Text Request
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