Objective: To investigate the postoperatively influence of lightweight mesh andheavyweight mesh in tension-free inguinal hernia repair. Methods:80cases of inguinalhernia patients were elected with informed consent protocol. then randomized into twogroups, the experimental group (40patents) which use lightweight polypropylene mesh,and the control group (40patents) which use standard polypropylene mesh. Lichtensteintension-free repair technique was performed on all patients. Take the serum of patientsbefore the operation, on the first and3rd day of the operation to test WBC,CRP,IL-6leveland then compare the difference of changes before and after the therapy between twogroups, an independent doctor evaluated the patents for postoperative groin pain, days inhospital, clinical recurrence, foreign body sensation, postoperative complications and,quality of life. Quality of life was assessed using Short Form36before operation and6months after surgery. Pain was assessed by means of a visual analogue scale2days and6months after surgery. The primary outcome measure was the feeling of a foreign body inthe groin at6months. Result: Some80hernias were randomized and included in theanalysis of perioperative data, and72were follow up for12months. There were nodifferences between the treatment groups with respect to days in hospital, operating time,postoperative WBC,CRP,IL-6level, postoperative complications (P>0.05), Use oflightweight mesh was associated with significantly less foreign body sensation and lowerearly infection rate (P≤0.05). Conclusion: Lightweight polypropylene mesh canobviously reduce the incidence of postoperative foreign body sensation and. Lightweightmesh may be preferable for Lichtenstein repair of inguinal hernia in terms of The stressresponse, inflammation. |