The-Clinical-Research-Of-Yiwei-Huacai-Decoction-to-Treat-Chronic-Atrophic-Gastritis-Type-of-the-Lack-of-Permits-for-Stomach-Yin

Chronic atrophic gastritis (CAG), is a common chronic diseases of digestive system disease, difficult to treat, severe CAG with severe intestinal metaplasia and severe dysplasia, closely related to the occurrence of gastric cancer. Modern medicine for chronic atrophic gastritis to symptomatic treatment and close follow-up based, it is often difficult to make the reversal of atrophic lesions. Numerous studies have shown that traditional Chinese medicine CAG efficacy, less side effects, showing their own unique advantages. Investigate the chronic atrophic gastritis TCM standardized treatment program, to develop a universal and effective traditional Chinese medicine formulations used in clinical, with the exact practical significance. This topic was reviewed on the basis of CAG progress in the past decade, carried out clinical studies of the the Yiwei cut side of treatment CAG.Objective:To observe the clinical curativate effect to treat of Weakness of the spleen and damp-heat stasis Syndrome of Chronic Atrophic Gastritis by Yiwei Huacai Decoction.and to explore its possible mechanism and to provide effective prescriptions for the clinical treatment of chronic atrophic gastritis.Methods:According to the randomized, controlled the principle, according to the diagnostic criteria, inclusion criteria, exclusion standard screening out of42cases of chronic atrophic gastritis, stomach yin deficiency patients,21cases divided into test group and control group of21cases, the two groups in age, gender, duration of disease, symptoms, signs, endoscopy, pathology, no significant differences (p>0.05). Experimental group I Yiwei cut side of a day, divided into2doses, control group I Weimeisu12a day,3times daily, two groups of three to one course of treatment. After the end of a course of treatment before and after the observation of two groups of patients with symptoms, signs, endoscopy, pathology, to determine efficacy.Results:(1) clinical symptoms, signs of efficacy:the experimental group to improve stomach pain, poor appetite Eat superior to the control group (p<0.05); to improve bloating, belching, acid reflux, dry mouth, mouth pain, noisy stool dry by efficacy (P>0.05).(2)The gastroscope efficacy:endoscopic gastric mucosal improvement in the experimental group than the control group (p<0.05).(3) a therapeutic:atrophy, intestinal metaplasia, the experimental group than the control group (p<0.05); dysplasia in terms of both efficacy no difference (p>0.05).(4) Yiwei of the CD soup no adverse effects were found in the clinical application.Conclusion:Through the correlation analysis, that Yiwei of the Conference on Treatment of this disease stomach yin deficiency is not only better clinical efficacy, but also to significantly reverse the pathological state of chronic atrophic gastritis, which further reveals Yiwei of the CD treatment of chronic atrophic gastritis is reasonable, and prompt the mechanism may be related with the disease resistance of the original microbial, anti-inflammatory and regulate immunity, improve gastric mucosal microcirculation and enhance the gastric mucosal barrier, scavenge oxygen free radicals, anti-tumor function.