| Objective: To study the relationship between the level of serum uric acid (SUA)andcoronary heart disease(CHD). Method: A total333cases received coronary angiographyand hospitalized in our department from January2010to June2011were enrolled. According tothe results of coronary angiography, the patients were divided into CHD group (n=180) andnon-CHD group (n=153). The CHD group was redivided into three subgroups with46single vascular lesion group,63double vascular lesions group and73multivessel vascularlesions group according to the scope of pathological changes. All the patients were dividedinto two subgroups: high SUA group (n=243) and normal SUA group (n=90). We recordedof the age, sex, smoking history, hypertension and diabetes mellitus history, then evaluateSUAã€FPGã€TGã€TCã€LDL-Cã€HDL-C of each group. Statistic analysis was done withSAS9.2software. Results:(1)The level of SUA in CHD group was significantly higherthan that of non-CHD group (P<0.05);(2)Detection rate of hyperuricemia was33.89%inCHD group, which was ignificantly higher than that of non-CHD group(18.95%, P<0.05);(3)The levels of SUA and FPG of single vascular lesion group werehigher than that of multivessel vascular lesions group;(4)The level of SUA wascorrelated with TG and negatively correlated with HDL-C, r was0.146and-0.188,P<0.05;(5)The number of coronary artery branches with lesions was correlated with thelevel of SUA (r=0.257, P<0.05);(6)Logistic regression analysis indicated that age, FPGand SUA were risk factors of CHD, and OR was4.013,3.108,1.782. Conclusion: Thelevel of SUA is closely related to the occurrence and development of CHD. |
