Analysis Of Risk Factors And The Clinical Features Correlated With Coronary Atherosclerotic Heart Disease

Objective： By retrospective analyzing relativity between Coronaryatherosclerotic heart disease and its some risk factors,such as gender,age,weight,low-density lipoprotein cholesterol,triglyceride，uric acid，glucose,smoking,blood pressure, and so on,to screen out the main risk factors correlated withCoronary atherosclerotic heart disease.At the same time，analyze and studyclinical character of Coronary atherosclerotic heart disease which containsclinical symptoms and the incidence of hypertention,diabetes mellitus,hyperlipidemia.Methods: One hundred patients with Coronary atherosclerotic heartdisease is the case.The control group include sixty patients who are not withCoronary atherosclerotic heart disease.These patients are from thecardiovascular treatment center medical group of the first hospital of JilinUniversity in2010January to2011December. A retrospective case-controlstudy is applied to analyze its some risk factors which are gender,age,bodyweight,low-density lipoprotein cholesterol,triglyceride， uric acid，glucose,smoking,and blood pressure by SPSS18.0for Windows statisticalsoftware with non-conditional Logistic regression model.χ2test of SPSS18.0for Windows statistical software is applied between the two groups ofdiabetes,hypertension,hyperlipidemia and the prevalence of overweight,smoking,etc to comparative analysis the differences between the twogroups.Also include recording and analysising clinical symptoms of onehundred patients with Coronary atherosclerotic heart disease.Results:1.The single factor non-conditional Logistic regression analysisshows that the factors include gender,age,smoking,low-density lipoprotein cholesterol, diabetes,hypertension have different degrees of positive correlationwith Coronary atherosclerotic heart disease (P<0.05);High density lipoproteincholesterol and Coronary atherosclerotic heart disease show a certain degree ofnegative correlation (P<0.05);But there is no significant difference inoverweight,uric acid between the two groups.Multivariate non-conditionalLogistic regression analysis which is applied among age,somking,low-densitylipoprotein cholesterol,diabetes, hypertension shows that these risk factors arestill elected and has a high degree of risk (P<0.05).2.The prevalence of the casein hypertension,diabetes mellitus，hyperlipidemia,overweight and smoking issignificantly higher than the controls.The difference is statistically significant.3.In100patients with coronary atherosclerotic heart disease patients withoutclinical symptoms in5cases, accounted for5%, with clinical symptoms in95cases, of which about55manifestations of angina pectoris, accounted for55%;25cases of myocardial infarction, accounted for25%,14cases showedischemic myocardial disease type, accounted for14%,1cases of sudden death,accounted for1%. Based on the comparison and analysis of100cases ofcoronary heart disease patients, the patients who complicated with diabetesmellitus found hypertension,dyslipidemia, LDL-C levels, angina, myocardialinfarction incidence was higher than that in non-DM group, DM group ofpatients with multivessel coronary artery disease rate (above2) wassignificantly higher than that of non-DM group.Conclusions:Gender,age,smoking, low-density lipoprotein cholesterol,diabetes, hypertension are closely related to Coronary atherosclerotic heartdisease and are highly risk(P<0.01). Patients with Coronary atheroscleroticheart disease are mostly with clinical and accompany hypertension,diabetes,hyperlipidemia.Prevalence of smoking and the proportion of obesity ishigher than the contorls. Based on the comparison and analysis of100cases ofcoronary heart disease patients, the patients who complicated with diabetes mellitus found hypertension,dyslipidemia, LDL-C levels, angina, myocardialinfarction incidence was higher than that in non-DM group, DM group ofpatients with multivessel coronary artery disease rate (above2) wassignificantly higher than that of non-DM group.