The Analysis Of The Risk Factors Of Coronary Atherosclerotic Heart Disease

Objective: Research the characteristics of coronary artery angiography in the CHD patients, analyze its relationship with risk factors or some clinical laboratory scores and explore the major risk factors of CHD in local area with the hope to identify and intervene in the major risk factors in early phase, and then reduce the occurrence of cardiovascular adverse events.Methods: The data were collected from 340 patients from January 2012 to December 2015 in The Fist Affiliated Hospital of Fujian Medical University, who accepted coronary angiography during hospitalization without serious diseases such as heart disease, hepatic failure, pulmonary infection, cancer and immunological diseases and so on. According to the results of coronary angiography, the patients were divided into CHD group and non CHD group. CHD group was divided into three groups which were named mild, moderate and severe according to the modified Gensini score. This study analyzed characteristics of coronary angiography, its relationship with risk factors or some clinical laboratory scores. The study also analyzed the relationship between risk factors and coronary artery lesions.Results: 228 patients were included in CHD group, whose average age was 63.69±9.336 years old. There were 175 males(76.8%) in the group. 112 patients were included in non CHD group, whose the average age was 60.59±10.728 years old. There were some differences between the two groups in male, age, history of diabetes, smoking history, WBC, NE, FIB and HDL-C. Male, smoking history and FIB were independent risk factors of CHD(? male=1.086,? smoking history=0.942,? FIB=0.837). The analysis of coronary angiography showing the most lesion vessels was LAD, RCA, LCX,LM in sequence. The more serious the coronary artery lesion was, the more the lesion vessel was. There were some differences among mild, moderate and severe in history of diabetes, smoking history, FIB, TC and LDL-C. History of diabetes, smoking, LDL- C and degree of coronary artery lesions were positively correlated. CHD patients who only had high blood pressure had the less serious vessel lesions(42.86%). The diabetes and degree of coronary artery lesions were positively correlated in patients with CHD and hypertension( ?=1.472,95%CI:1.844-10.299).Conclusion:The majority of CHD patients, who were generally elder than non CHD patients, were male. Smoking history, male and FIB were independent risk factors of CHD.The degree of coronary artery lesion severity related to history of diabetes, smoking history, FIB, TC and LDL–C. History of diabetes, smoking history and LDL-C were independent risk factors of the degree of coronary artery lesion severity. CHD patients who only had high blood pressure had less serious vessel lesions. CHD patients with hypertension complicated with diabetes or smoking history were the high-risk group of severe coronary lesions.