The Clinical Research On Primary Dysmenorrhea (Syndrome Of Cold Coagulation And Blood Stasis) With Jingtongshu Grain

Object ivePrimary dysmenorrhea is a common, multiple disease of women with menstrual cycle, and persistent seizures,The main purpose of this subject in Ⅱ trial on the basis of further validation of traditional Chinese medicine by Jingtongshu Grain treatment of primary Clinical efficacy (Cold coagulation and blood stasis type) and safety, toxic side effects and adverse reactions and the system of evaluation.Scientific guidance for clinical dosageMethodThis experiment was used randomized, blind, parallel controlled, multicenter study method. Study of medical records from2008February-December2008in ubei Hospital of Traditional Chinese Medicine in gynecological outpatients with a diagnosis of primary dysmenorrhea (syndrome of cold coagulation and blood stasis) patients, a total of80patients, aged14-30years old, by3:1ratio were randomly divided into the treatment group (Jingtongshu Grain) and the control group (Yueyueshu granules), the experimental group60cases,20cases of the control group.Results:1:Comprehensive efficacy comparison in60cases in the treatment group,20cases in the control group, both the complete medical record writing. Drug treatment for two months Menstrual cycle, the treatment group of60cases,10cases were cured,20cases effective,7cases are invalid, cure rate16.67%, effective in33.33%, the total effective rate was88.33%; the control group of20cases,7cases were cured,9cases effective,3cases are invalid, cure rate35%, effective in45%, the total efficiency of85%, by statistical analysis, P>0.05, the difference was not statistically significant.2. Treatment group and control group before and after treatment,Chinese medicine symptom total score, P<0.01There are significant differences in statistical analysis, description After treatment, the symptoms were significantly improved. After treatment, the two groups compare TCM symptom total score P>0.05, the difference was not significant.3.Pain cure curative effect comparison:After two menstrual cycle treatment, compared to the lower abdomen pain in comparison the treatment group of60cases,10cases were cured,8cases were invalid, The cure rate was16.67%, the total effective rate was86.67%; the control group9cases were cured,4cases were invalid, the cure rate was45%, the total efficiency of80%, comparison between two groups,P>0.05, have no significant difference4. Comparison of Chinese medicine of the other symptoms:use2menstrual cycles after the treatment group before and after treatment, the symptom scores were significantly decreased,P<0.01, illustrated by Jingtongshu Grain in treating primary dysmenorrhea symptoms were significantly effect the. The control group before and after treatment the symptom scores also decreased, P<0.01. After Jingtongshu Grain in treating primary dysmenorrhea symptoms were significantly effect the P>0.05, Two groups of treatment of primary dysmenorrhea, compared to other symptom curative effect, no obvious difference had no obvious difference, two groups of treatment effect.5. Safety:two groups of patients in medication during the observation period without obvious adverse reactions and side effects, after treatment of gynecological examination,B ultrasound examination, blood, urine, stool examination, liver function, renal function, electrocardiogram and general physical examination did not change significantly, suggesting that the two groups of drugs are toxic and side effect, safe and reliableConclusion:By Jingtongshu Grain can be effective in the treatment of primary dysmenorrhea (syndrome of cold coagulation and blood stasis), can significantly reduce the female menstrual pain and discomfort, and the clinical curative effect is reliable, no obvious toxic side effect, good security, can significantly improve patient quality of life, improve the standard of living, worthy of clinical application.