Clinical Analysis On Surgical Treatment Of Glioma-Triggered Epilepsy With The Application Of Electrocorticography

Objective:To explore the methods and effect of surgical treatment of glioma-triggered epilepsy with assistance of Electrocorticography(ECoG).Methods:Clinical data of76cases were retrospectively analysed and divided into2groups according to different surgical methods:46cases were resected with the assistance of neuronavigation and intraoperative ECoG were performed to determine the location and the range of epileptogenic zones,epileptogenic zones in non-functional areas were removed while in functional areas cortical thermo-coagulation was performed (Group A);30cases were resected with the assistance of neuronavigation (Group B).1-2year follow-up, the incidences of epilepsy of the2groups were compared.Results:1month after operation,there were13patients with epilepsy,among which3cases(6.5%) were in Group A and10cases(33.3%) in Group B,indicating that statistically significant difference was obtained in2groups(Chi-sqaure=7.41,P<0.05).3months after operation,there were12patients with epilepsy,among which5cases(10.9%) were in Group A and7cases(23.3%) in Group B(no significant difference obtained,Chi-sqaure=2.12,P>0.05).1year after operation,there were14patients with epilepsy,among which6cases(13.0%) were in Group A and8cases(26.7%) in Group B(no significant difference obtained,Chi-sqaure=2.24,P>0.05).Conclusion:The application of ECoG for surgical treatment of glioma-triggered epilepsy can reduce the incidence of postoperative early epilepsy.