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Nourish Yin Eliminating Phlegm To Treatments To Diabetes Of Peripheral Neuropathy

Posted on:2013-03-12Degree:MasterType:Thesis
Country:ChinaCandidate:Z W ZhuFull Text:PDF
GTID:2234330374451343Subject:TCM clinical basis
Abstract/Summary:PDF Full Text Request
This article is based on the traditional Chinese medicine theory as the guide, combining modern medical knowledge, through the literature review, the theory discussion, animal experiment and research, diabetic peripheral neuropathy (diabetic peripheral neuropathy, DPN) Yin deficiency, the pathogenesis of qi stagnant essence and nourishing action principle and method of resolving phlegm using points, studied. Think the disease to the deficiency of Yin qi stagnant, for standard, Yin qi stagnant and they are the cause of this disease to occur development plays an important role. With the function of Yin eliminating phlegm to consolidate, eliminating phlegm to take temporary solution the function, is an important treatment alleiating DPN. In animal studies, chain with urea by lethal injection in meat (STZ) bacteria heightening sugar high fat diet establish rat of peripheral neuropathy in diabetes pathological model, using immunohistochemical, biochemical and other methods, the research from different aspects nourish "Yin" eliminating phlegm to represent increase the liquid tonga melon to rat semen party DPN blood sugar, blood fat and siatic nerve conduction speed, nerve growth factor receptor and the influence of the TrkA index, and reveals the increasing fluid tonga melon trichosanthis alleiating DPN party mechanism of action, and a comprehensive evaluation method of eliminating phlegm to nourish "Yin" alleiating DPN curative effect. The results showed that:(1) the diabetic rats of peripheral neuropathy damage model copy success;(2) increasing fluid tonga melon has certain glucose-lowering trichosanthis party role and lipid-lowering role;(3) increase fluid tonga trichosanthis party can improve the melon diabetic rats sciatic nerve conduction speed; To nerve growth factor receptor also TrkA have certain effect, can improve the neural function.The results for diabetic peripheral neuropathy Yin deficiency and pathology of the essence and the qi stagnant Yin Yin expectorant roles of law principle to provide theoretical and practical basis for using the theory of TCM differentiation diabetic peripheral neuropathy is of certain reference for further study the disease made beneficial exploration.
Keywords/Search Tags:nourishing yin, ransforming phlegm, DPN, theory research, experimental study
PDF Full Text Request
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