The Clinical Characteristics And Diagnosis Of Liver Rare Type Benign Tumors

Objective: Even though the radiological examinations have been developed so dramatically in the last decades, it is still a difficult thing to make preoperative diagnoses to liver tumors because of the diversity. They shared common radiological features, which caused the preoperative diagnoses more complicated. Different liver tumors need different treatments, and the prognoses are different as well. For many liver benign tumors are difficult to be preoperatively diagnosed. They might be misdiagnosed as malignant tumors, which caused the unnecessary treatments, it would be a disaster to the patient economically and mentally. On the contrary, if the malignant one was misdiagnosed as a benign one, the patient would lose the optimal treatment window. In this study, to improve the rate of the preoperative diagnose, the clinical data, diagnostic and therapeutic processes of the rare type benign tumors of the liver were analyzed.Methods: To analyze 27 patients with rare type liver begin tumors who were admitted in the affiliated first hospital Dalian medical university, from 2002 to now, the diagnoses were conformed by pathological examinations, including hepatic adenoma 4 cases, FNH 12 cases, liver harmatoma 4 cases, liver inflammatory pseudotumors 6 cases, liver lipoma 1 case. The tumor etiology, pathology, clinical manifestations and radiological examination results were studied retrospectively in this paper.Results: In 27 cases, male 10 cases, female 17 cases, age ranges 18-76 year-old, mean age is 48 year-old. 4 cases had HBV disease history and 2 cases liver cirrhosis. The main complains: tumor was found occasionally in physical examination 17 cases (63%), uncomfortable feeling in upper right abdomen 10 cases (37%), respectively. Only one patient got a high level of serum AFP(<200ug/ml), which return to normal range after the surgery. Clinically, single lesions were found in 88.9% of cases, the other 11.1% of cases were displayed as multiple lesions. Lesions locations: 37% in the left lobe, 55.6% in the right lobe, 3.7% in the caudal lobe, 3.7% located both left and right lobes. 17 (63%) lesions were correctly diagnosed before surgery. The diagnoses were made 0 by ultrasound, 4 cases by CT scan, 11 cases by MRI and 2 cases by liver biopsies.Conclusions: The rare type benign tumors in the liver were easy to be misdiagnosed in the clinic, because of their undistinguished clinical features. The diagnosis could be made correctly depending on the foundation of being familiar with the clinical features of the disease, improving serum AFP detection, improving ultrasound, CT, MRI examinations, and the most important, combining the patient disease history.