Clinical Observation Of Ischemic Colitis With Compound Danshen Injection Plus Gushenchang An Capsule

ObjectiveThis subject observed the clinical efficacy that taking compound danshen injection with Gushenchang an capsule to treat the patients with ischemic colitis, discussed its pharmacological effects, and evaluate the clinical practical value.MethodSelect met inclusion criteria ischemic enteritis 60 cases, patients were randomly divided into trial group and control group each 30 cases. The observation group give compound danshen injection 30ml to join 10% glucose solution static drop 250ml once a day, and continued drug use 1-2 weeks, one week later Gushenchang an capsule 0.4 g orally, tree times a day. The control group give 0.9% saline 30ml to join 10% glucose solution 250ml static drop one times per day, and continued drug use 1-2 weeks. This period both groups may affect drug discontinuation of other drugs, give curative general support treatment, pay attention to rest, two groups of patients before and after treatment, liver and kidney function life signs, and monitor commonly observed both groups of patients before and after the treatment symptoms, defecate, colonoscopy changes such as.Results 1, the disease occur in the elderly, female patients with more than men, and 80% of patients have the basic diseases, such as atherosclerosis, vasculitis, tiny vasospasm, low blood pressure, etc, vascular factors and constipation and diarrhoea putrified pressure caused by rising and dilated bowel peristalsis enhancement after eating, oxygen such as increased demand dilated bowel itself to a combination of factors, cause a period of colon absolute or relative ischemia, happen tissue damage.2, the disease occurs in descending colon and the sigmoid colon (97.3%), only a handful of cases are in the ascending colon and rectal (3.34%), another part'occurs in colon spleen area (11.6%7).3, two groups of patients before and after the treatment are both better defecate occult blood, and before treatment was statistically significant comparative differences (P< 0.05), the observation group improving effectiveness than control group.4, after treatment, the two groups of patients with symptoms than total score before treatment are improved, significant difference (P< 0.01), including the observation group in improving abdominal pain, blood stool, diarrhea symptoms than in control group (P< 0.05).5, after treatment, the two groups of colonoscopy mucosal lesions are better than before, in alleviating bowel mucosal lesions, the observation group than in control group, with significant difference difference (P< 0.01).6, Comprehensive effect comparison, the observation group in 30 cases, powerfully 20 cases, effective.8 cases, invalid 93.33% in 2 cases, the total effective. The control group,30 cases of 13 cases, effective got 13 cases, invalid 4 cases failure; the total effective intellectual. The observation group clinical curative effect, significant efficiency than control group was better than control group (P< 0.05).7, and the observation group average discharge time 10+0.37 days, the treatment group average discharge time 14.2+0.56 days, the observation group discharge time is short, the control group was statistically significant difference (P< 0.05).Conclusioncompound danshen injection joint GuCan bowel Ann treatment of ischemic colitis is feasible, and the bowel mucosal lesions in symptoms, the improvement of and the length of time, better results than those relatively short, the total effective rate of western medicine therapy group slightly above western medicine therapy group alone.