The Clinical Study Of Treatment In The Mixed-predominant Irritable Bowel Syndrome By Reconciliation Of The Spleen And Liver,the Method Of Cold Combined With Heat

Purpose This issue mainly researches the mechanism and treatment of mixed-predominant Irritable Bowel Syndrome(IBS-M).Based on the pathogenesis the liver and spleen are not adjusted in IBS, we proposed the mechanism of mixed cold and heat, and combined with clinical studies,to evaluate the effect of traditional Chinese medicine in treating IBS-M.Method 56 patients with IBS were divided into 2 groups at random. The observed group(30 people) took probiotic three times with oral medicine one bag each day, the control group(26 people) took probiotic three times each day. Every patient should be asked for filling out a form before and after the treatment:The Irritable Bowel Syndrome Quality Of Life (IBS-QOL). The course of treatment was 4 weeks. We recorded the patients'clinical symptoms when before treatment, the first 2 weeks and after treatment, then follow-up month later. In the end we analyzed the data.To evaluate the effects by comparing changes of symptom score and quality of life score.Results 1.The treatment group's total effective rate was 93.33%,while the total group was 61.54%.Compared with the latter, the former was better (P<0.05).2.Comparison of the efficacy of IBS symptoms:most symptoms in both groups improved significantly after treatment(P<0.05),particularly in the stool,abdominal pain, poor bowel movement aspect,the treatment group was prior to the control group(P＜0.01) In the syndromes of Chinease medicine efficacy,both group improved compared with before(P<0.01),and the treatment group was significantly different compared with the control group(P<0.01),which suggested the Chinease medicine is more effective than the control group in improving clinical symptoms of patiens.3.Quality of life of patients:The IBS-QOL scores showed that the two groups were significantly different after treatment(P<0.05).By further comparing the differences of the improvement of dimensions,the results indicated that the treatment group was better than the control group in the following four dimensions: Irritability(Q1), Conflict Behavior(Q2), Physical Role(Q3), Health Concerns(Q4) (P<0.05).Conclusion After treatment, patients' symptoms scores and quality of life scores all improved in varying degrees, and the treatment group was better than the control group.This study suggests that Chinease medicine can not only significantly improve abdominal pain, poor bowel movement, dry or loose stool and other major symptoms in patients with IBS,but also improve the mental, psychological status, social roles and other quality of life. Reconciliation of the spleen and liver, the method of cold combined with heat have certain advantages in treating IBS-M,and this method is valuable to give further study and exploration.