Eliminate Water Side In Combination With Cisplatin Pleural Perfusion Clinical Observation Of Treatment Of Malignant Pleural Effusion

MPE(Malignant pleural effusion) is a common complication of advanced cancer,most of disease progression or recurrence of the results,but also as the first clinical cancer patients,patients with serious impact on survival and quality of life.Once there,had surgery and radiotherapy indications,even if given chemotherapy,immunology and medicine in combination therapy,efficacy is not ideal.A large number of pleural effusion can cause respiratory and circulation insufficiency or failure, repeatedly pumping liquid protein can lead to the loss,illness and accelerate the eterioration of death,how to effectively control the treatment is always one of the difficulties.Of the reported treatment of the disease at home and abroad means a lot,but the effect is not satisfied with conventional chemotherapy drugs in the chest,side effects, Tixu,elderly patients often unbearable.Chinese medicine treatment of this disease is a major complication of tumor characteristics,past more reported in the literature, traditional Chinese medicine in the treatment of MPE,and reduce the toxicity of chemotherapy,chemotherapy improved completion rate,alleviate symptoms,improve quality of life.This is the first use of standard clinical symptom score scale,before and after treatment to score margin of quantitative data,class information and Evaluation of the quality of life to improve the situation by Anova analysis from the Chinese attenuated to improve efficiency,and synergies with the modern medicine perspective,given China Academy of Traditional Chinese Medicine Hospital oncology Guang'An Men from March 2007 to March 2009 of the 81 treated patients with MPE patients(42 patients with the treatment group,use basic therapy+pleural perfusion with DDP+The elimination of water oral:and the control group,39 patients,use basic therapy+pleural perfusion with DDP) prospective clinical intervention,with a view to further enhance the Chinese medicine treatment of MPE clinical efficacy.Chinese Consumers water for the simple clinical application,as well as chest with DDP in the treatment of malignant pleural effusion provide clinical basis for the large-scale clinical application provide an initial basis.The results show that:①baseline information before treatment comparison showed:two groups in age,gender,MPE of the illness,Chinese medicine syndrome,KPS score areas showed no significant difference(P>0.05),and comparability.②effect of the recent assessment, the treatment group and the control group efficiency(CR + PR) were 71.43% and 64.10%,the statistical analysis,no significant difference(P=0.103).③quality of life of the assessment results,two clinical benefit rate (increase+stable) were 90.1%and 53.8%,the statistical analysis,there are significant differences(P=0.01).④clinical symptoms improve the situation,the treatment group before and after the symptom score margin to 2.95±2.871,the control group before and after the symptom score margin to 0.1±3.21,the two groups,there are significant differences(P=0).⑤adverse reactions,ⅢThere were no adverse reactions of the above, no kidney toxicity.Based on the results of the study,we believe that the Chinese onsumers water,combined with DDP chest in the treatment of MPE,although no obvious effect of the recent increase(P>0.05),but to improve the quality of life of patients with clinical symptoms and have practical significance,Worthy of further promotion.