Serum Bilirubin With Coronary Heart Disease, Hyperlipidemia, Coronary Angiography And Tcm Syndrome-related Research

Objective : Through relative researches of TCM type of coronary heart disease and serum bilirubin ,blood fat, coronary arteriongraphy, trying to find some specific objective indexes and leading them to the TCM differentiation of CHD. These indexes which make differentiation more objective and provide a reliable basis for treatment and prognosis.Methods : Totally 150 patients of CHD are divided into six groups according to the standardization of syndrome of the guide book of new TCM pharmacological clinical research (2002 version).Dividing the patients by differential standard and collecting their serum bilirubin ,blood fat and 60 patients' coronary arteriongraphy results (those who have accept coronary arteriongraphy ).to analyze the distribution regularity or TCM patterns of CHD and its relationship to the levels of these tests results.Results : 1. Arrange six TCM syndrome patterns of CHD according to their constitute ratio in order : stagnation of heart-blood syndrome > stagnation of phlegm of heart meridian syndrome > deficiency of vital energy and stagnation of blood syndrome > deficiency of both vital energy and yin syndrome > deficiency of both heart-Yin and kidney-Yin syndrome > stagnation of both vital energy and blood syndrome. 2. The research of the topic found that serum bilirubin of stagnation of heart-blood syndrome group of CHD obviously lower than other groups, stagnation of phlegm of heart meridian syndrome group is the next in order, compared with deficient syndrome groups ,the difference was statistically significant . 3. The TG , TC and LDL-C of stagnation of phlegm of heart meridian group is higher than other groups ,through statistical treatment , the difference have significant deviation . 4. The main pathological change of coronary artery of stagnation of phlegm of heart meridian, stagnation of heart-blood and stagnation of both vital energy and blood is multitude branches , and the main pathological change of coronary artery of deficiency of vital energy and stagnation of blood , deficiency of both vital energy and Yin group and deficiency of both heart-Yin and kidney-Yin group is simple branch . The main change of sthenia syndrome groups is serious and occlusion , but the affection of deficient syndrome groups is more lighter . Conclusions : 1. The distribution and change of syndromes of CHD is regular . 2. The serum bilirubin of all sthenia syndrome groups is significantly lower than deficient syndrome groups ,so serum bilirubin can be used a point of reference to CHD syndrome differentiation and treatment. 3. Blood fat, especially TG , TC and LDL-C can be used as a reference indicator for differentiation and treatment in clinical . 4. The branches and degree of pathological change of coronary artery also can be used as a reference indicator for differentiation of CHD between sthenia syndrome and deficient syndrome .