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Making Mold Lotion Treatment Vulvovaginal Candida Yeast Disease Clinical Research

Posted on:2009-12-03Degree:MasterType:Thesis
Country:ChinaCandidate:L LinFull Text:PDF
GTID:2204360245959050Subject:TCM gynecology
Abstract/Summary:PDF Full Text Request
Objective:To investigate the treatment of mycophenolate lotion vulvovaginal candidiasis leave of the efficacy and safety of mycophenolate lotion system for theclinical application of scientific basis.Method:Vulvovaginal Candida 65 patients were randomly divided into two groups: theexperimental group was 35 cases, 30 cases of the control group. Mycophenolatesystem to the treatment group Lotion (LDC Fuling, Osthol, the flowers, alum,Phellodendron, searching bone winds and wild chrysanthemum, realgar, Kushen,etc.) washing the vagina, on the 1st 2nd, seven days for a course of treatment,menstrual stop used. Control group Jieeryin vaginal washing lotion day 1, 7 daysfor a course of treatment, menstrual out. Local signs of vulvovaginal,cleanliness of the vagina changes in the rate of negative pathogens and ananalysis of the effects of comparison, the safety and observing the changes inindicators for statistical analysisResult:1. Mycophenolate lotion system in the treatment group vulvovaginal Candida disease cure rate is 68.57%, the effective rate is 17.14%, the total efficiency of 91.43%; Jieeryin lotion cure rate for the control group, 36.67%, significantly efficiency 20% of the total efficiency of 73.33%, the clinical efficacy between the two groups statistically significant difference (P<0.05).2.Two vaginal drug could significantly improve the cleanliness (P<0. 01), and between the two groups before and after treatment compared changes in vaginal cleanliness there was no significant difference (P>0. 05).3. Streptomyces are two drugs on the obvious negative effect of the treatment group was 71.43% negative, the negative control group rate of 70.00%, between the two groups had no significant difference (p>0. 05). 4. Two Group drugs can significantly improve genital, vaginal local signs (p <0.01) after treatment drug effects between the two groups showed no significant difference (p>0.05).5. Two drug could significantly improve the clinical symptoms such as vaginal discharge volume, perineum Yang Tong, and so on, before and after treatment with significant differences(p<0.01) between the two groups before and after treatment comparisons showed that(p<0.05). Other symptoms to improve the therapeutic effect of no significant difference (p>0. 05)6. safety testing: before and after treatment were blood, urine, liver function, renal function abnormalities detected no change (p>0. 05), that system mycophenolate lotion safe, effective and non-toxic.Conclusionsystem mycophenolate lotion is effective in treatment of vulvovaginal Candidadisease, can significantly improve the cleanliness vagina, the vulva, vaginalocal clinical signs and symptoms, overcast high rate of clinical applicationof safe, effective and without adverse reaction, it is worth clinicalapplication.
Keywords/Search Tags:vulvovaginal Candida disease/Chinese medicine treatment, clinical research, Qingrejiedu,insecticidal, mycophenolate Lotion
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