Observation Of The Clinical Efficacy Of The Treatment Of Acute Mild And Moderate Traumatic Brain Injury Pinggan Yang

This thesis can be devided into two parts: the one is the review summaries, which tell us the understanding treatment and the lately progresss in the recently ten years about craniocerebral injury in the light of modern medicine and traditional medicine respectively, the other one is the clinical studies.From modern medicine, craniocerebral injury is caused by outside violence and its occurrence and development depend on the factor and property of the damages. there are a lot of methods to classify the craniocerebral injury. In the light of mechanisms , it can be devided into primary brain injury and secondary brain injury. The former is the result of direct or indirect violence in the head . Direct hit in the head can lead to three kinds of damages including injury of acceleration , injury of deceleration and crush injury. Indirect violence also results in serious brain injury, such as whiplash injury craniocervical junction injury and chest-crushed injury. The latter includes traumatic cerebral edema and tardive neuronic damages . Damages of blood-brain barrier, calcium overloading, increase of oxyradical , lipid peroxidation are the reasons that develop the traumatic cerebral edema. Abnormal transmitter or acceptor , lipid peroxidation and calcium overloading also can make neuron necrosis or apoptosis.The patients with opened craniocerebral injury or those with closed craniocerebral injury with intracranial hematoma need operating. A lot of craniocerebral injury patients need non-operation. They always need to be lowered intracranial pressure and they are treated with ehydrater, hormone , oxygen,lytic cocktail or hypothermia ,etc. Sedative ,anti-epileptic ,NSC transplanting ,antibiotic, nutritional support and the therapy of complication are of importance to them.In traditional medicine, the principles of craniocerebral injury are founded gradually during long term clinical practice, and improved in every dynasty. The second part of the review summarizes include pathogeny, nosogenesis, symptom-complex summary and dialectical treatment in TCM.