Clinical and experimental study had been made about hyperthyroidism(Graves disease) treated by Xie Huo Xiao Ying granule in the article.SUMMARIZATIONTrough systematic reviewing and analysis defined that hyperthyroid (Graves disease) was belonged to traditional Chinese Medicine' s "Ying Disease". Through the results of summarizing experience of successive doctors about pathogeny , mechanism, set forth professor Wang Xu' s science thought about "deficiency of yin is the fundamental, stagnation of heat is the superficiality", and establish principles of the treatment.CLINICAL RESESRCHWe formulated cases selection and curative effects judgment standards according to concerned standards. Patients must be not only conformed to western medicine' s hyperthyroid (Graves disease) but also conformed to TCM' s deficiency of yin and stagnation of heat. The 50 cases were randomly distributed into TCM group and western medicine group. The curative time was 3 months. Through analyzing clinical symptoms , weights , serum thyroid hormone and throid-related antibody and etal, we concluded that TCM Xie Huo Xiao Ying granule group was better than western medicine in increasing weight, improving clinical symptoms , reducing thyroid hormone and etal. Moreover it could reduce the toxicity of western medicine. Clinical curative effects was stabilized and reliable.EXPERIMENTAL RESEARCHWe successfully made rats model of hyperthyroid after consulting related documents. The rats were randomly distributed into normal group , model group , western-medine group and TCM-western-medicine combined group. Accomplishing alot of experiments such as outward appearnce, body weight, heart rates, serum TT3, TT4, TSH, FT3, thyroid-related antibody, cytokines and etal . Observing the effects of TCM Xie Huo Xiao Ying granule and Researching the action mechanisms of TCM Xie Huo Xiao Ying granule. |