| Objective:To study the clinical efficiacy and pharmacological mechanism of Qubai Dection combined with Ver-nohia anthelmintica Willd (VW) injection in Vitiligo with Yin Deficiency of Liver and Kidney.Methods:70 patients with Vitiligo were divided into two groups randomly, treatment group,controlled group, they were both 35 cases.The treatment one added to oral Qubai Dection combined with Ver-nohia anthelmintica Willd (VW) injection, the controlled added to Ver-nohia anthelmintica Willd (VW) injection.We observed three monthes and recorded of changes in skin lesions monthly.Results:After 3 monthes,observe the clinical efficacy.In treatment group which had 33 cases,clinical cure results had been achieve in 5 cases,notable effective results in 9 cases and effective results in 11 cases,while noneffective results in 8 cases,the response rate was 75.76%. In controlled group which had 34 cases,clinical cure results had been achieve in 2 cases,notable effective results in 7 cases and effective results in 9 cases,while noneffective results in 16 cases,the response rate was 52.94%. Statistic analysis on clinical efficacy was compared in two groups by statistical software monthly. In the second month, there were considerable differences between two groups(p<0.05).In this treatment,they all didn't appear significant adverse reaction.Conclusions:Using Qubai Dection combined with the Ver-nohia anthelmintica Willd (VW) injection had the more prominent benefit in patients with vitiligo planae than the controlled group,and the onset time was more earlier. |
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