The Clinical Research On The Effect Of Qing Re Xiaozheng Fang And Hua Yu Zhi Tong Fang In Treating Adenomyosis

Objective:Observe the clinical curative effect of QingReXiaoZheng Fang combined with HuaYuZhiTong Fang, which is applied to treat adenomyosis, the stagnation-excessive heat type, and explore its work mechanism.Methods:We totally observed 60 patients of adenomyosis and it was divided into two groups randomly. The treatment group take QingReXiaoZheng Fang combined with HuaYuZhiTong Fang at stage, while the control group takes SanJieZhengTong capsule and DanEFuKang paste at stage, which are compared to observe their curative effects and impacts on thromboxane TXB2 and prostaglandin6-k-PGF1(?),PGE2.Results:After treatment, the syndrome score of the two groups has significant differences (P＜0.05 or P<0.01). The thromboxane TXB2 level of the two groups is obviously decreased after treating, which has significant differences compared with its original level (P＜0.05) and the control group (P＜0.05). The PGE2 level is decreased of the two groups after treating, which has significant differences compared with ex-treatment (P＜0.01) and the control group (P＜0.01).Conclusion: QingReXiaoZheng Fang combined with HuaYuZhiTong Fang has better effect in treating adenomyosis. The mechanism maybe has relation with the patients'high blood coagulation and vascular contraction, the decrease of the hyperplasia and inflammation of ectopic endometrial, adjust the blood prostaglandin etc to improve the syndromes.