Study On TCM Syndromes And Related Factors Of Diabetic Peripheral Neuropathy

Purpose:Analysis of TCM Syndrome Distribution, and investigate Patient-related clinical data to explore the correlation related indicators with various syndromes between to summarize TCM Syndrome Distribution, understand the hazardous constituents in various syndromes specific Performance, and thus its development changes do in-depth analysis and exploration of TCM treatment of DPN to Provide theoretical and clinical foundation.Material and method:from January 2015 to January 2016 with diabetic Peripheral neuropathy Patients in our hospital 160 cases of the study, all Patients were based on "TCM Diabetes Prevention Guide" Chinese Medical Association in 2007 issued by diabetic Peripheral neuropathy TCM dialectical and related diagnostic criteria "TCM Diagnosis" diagnosis, the diabetic Peripheral neuropathy Patients were selected syndrome type that is ASDP, Qi Deficiency, Yin blood stasis syndrome, yang and blood stasis syndrome, Phlegm stasis syndrome five groups, records of all age, gender, BMI, diabetes duration, Hb A1 c, triglycerides, total cholesterol, high density lipoprotein, low-density lipoprotein and other related indicators, correlation analysis and different type of traditional Chinese medicine with various indicators.Results: 1. The selected 160 patients with DPN, 64 cases of male, female 96 cases, accounted for 40% and 40% respectively. Of kidney deficiency syndrome in 52 cases(32.5%); Phlegm and blood stasis resistance network card 32 cases(20%); Qi deficiency blood stasis, 28 cases(17.5%); Yin deficiency and blood stasis syndrome in 48 patients(30%). Sex ratio at different syndrome types in patients with no obvious difference, no statistical significance(P>0.05). 2. The comparison between the two groups of two, kidney deficiency syndrome and Yin deficiency and blood stasis syndromes age of Qi deficiency and blood stasis syndrome compared with significant difference was statistically significant(P<0.05), suggesting that the kidney deficiency syndrome group of younger age Yin deficiency and blood stasis syndrome, Qi deficiency blood stasis. Phlegm and blood stasis resistance compared the age of Qi deficiency and blood stasis syndrome significant difference was statistically significant (P<0.05); The liver and kidney deficiency syndrome, phlegm and blood stasis resistance network age compared with no significant difference between the two groups(P>0.05). Qi deficiency and blood stasis syndrome, Yin deficiency and blood stasis syndrome compared to age, there was no significant differences between the two groups(P>0.05). 3. The syndrome type in patients with body mass index, phlegm and blood stasis resistance winding Qi deficiency syndrome > Yin deficiency and blood stasis syndrome of blood stasis syndrome > kidney deficiency syndrome. Comparison between two groups indicates the phlegm and blood stasis resistance collaterals syndrome and liver and kidney deficiency syndrome group compared with significant difference(P<0.01), phlegm and blood stasis resistance network card group difference compared with other groups(P<0.05), liver and kidney deficiency syndrome of Qi deficiency and blood stasis syndrome group compared with significant difference(P<0.05), kidney deficiency syndrome and Yin deficiency and blood stasis syndrome group compared with significant difference(P<0.05), Qi deficiency and blood stasis syndrome with Yin deficiency and blood stasis syndrome group compared with no significant differences(P>0.05). 4. Each card type course of the disease, patients with kidney deficiency syndrome > phlegm and blood stasis resistance winding > Yin deficiency and blood stasis syndrome > deficiency of blood stasis. Comparison between the two groups of two, kidney deficiency syndrome course of Qi deficiency and blood stasis and Yin deficiency and blood stasis syndrome compared with significant difference was statistically significant(P<0.05).And kidney deficiency syndrome and phlegm and blood stasis resistance compared the course there was no significant difference(P>0.05).Collaterals syndrome and phlegm and blood stasis resistance between Qi deficiency and Yin deficiency and blood stasis syndrome of blood stasis syndrome is also significant difference compared with statistical significance(P<0.05). Qi deficiency and blood stasis syndrome with Yin deficiency and blood stasis syndrome group course compared with no significant differences(P>0.05). 5. Each card type related indicators such as fasting blood glucose, blood sugar 2 hours after meal blood sugar, Hb A1 c, the results show that Yin deficiency and blood stasis syndrome in patients with fasting blood glucose, blood sugar 2 hours after meal for all card type in the highest, and significant difference compared with patients with liver and kidney deficiency syndrome group(P<0.05).Different syndrome types in patients with Hb A1 c were higher than normal, highest in patients with Yin deficiency and blood stasis syndrome, phlegm and blood stasis resistance network times, the lowest liver and kidney deficiency, Yin deficiency and blood stasis syndrome and kidney deficiency syndrome group patients were compared with significant difference(P<0.05), and the rest is no significant difference between groups(P>0.05). 6. Each card type blood lipid related indicators such as TC, TG, HDL-C compared with LDL-C, the results show that the TC, Yin deficiency and blood stasis syndrome group of high TC, Qi deficiency and blood stasis, liver and kidney deficiency syndrome group compared significant difference was statistically significant(P<0.05), compared with phlegm and blood stasis resistance network card group difference was not significant(P>0.05), and Qi deficiency and blood stasis syndrome group, liver and kidney deficiency syndrome and phlegm stasis blocking collaterals syndrome group of comparison difference between three groups was not significant(P>0.05). LDL- C, to Yin deficiency and blood stasis syndrome group is highest, Qi deficiency and blood stasis syndrome group is significant(P<0.05), and the rest was no significant difference between groups(P>0.05).TG, HDL-C, phlegm and blood stasis resistance network card set of TG, HDL-C values were higher, but the two comparative differences between groups were not significant(P>0.05).Conclusion: 1.TCM syndrome of DPN distribution, Percentage of the four groups from high to low are: Kidney deficiency syndrome,deficiency blood stasis syndrome, Phlegm and blood stasis resistance network card, Qi deficiency and blood stasis syndrome. 2.Liver and kidney deficiency type diabetes had longer duration of peripheral neuropathy and older. 3.Patients with phlegm and blood stasis resistance type winding average BMI is significantly higher than other groups. 4.Between different syndrome types all had different levels of blood sugar, blood lipid abnormalities.