| Objective:Analyses the clinic data of 85 patients who are suffered in ulcerative colitis (UC) in our hospital, to study the relation of the different syndromes in traditional Chinese medicine (TCM) in the gender, ages, area, course, occasions, stages, types, indexing, main symptoms, extent of disease, lab examinations, expressions in enteroscopy, the different levels of histopathology, expressions out the colon, complications, and the situations of using Chinese herbs. Hope to improve TCM understanding of the disease and to guide the clinical treatment.Methods:1.Source:After concluding, we choose some medical records of the patients who were diagnosed to UC from digestion department in Subsidiary Hospital of Chengdu University of Traditional Chinese Medicine (SHCDUTCM) during Mar.1st,2013 to Dec.30th,2015.2.Guided by 2-3 associate chief physicians and much higher level doctors, we parted different syndrome differentiations in TCM according to the standard of syndrome differentiation in TCM made by The view of the consensus of treatments in TCM in treating Ulcerative Colitis of the Chapter of Digestive Disease in China Association of Chinese Medicine,2009. Also we made western medical diagnoses, the stages, types, and the indexing by the standard of western medical diagnoses in The view of the consensus in diagnosing and treating of inflammatory enteropathy,2012, Guangzhou. Reorganized the range of medical records by Montreal classification method. Graded the level of activity in histology of selected medical records. In addition, we recorded the ages, gender, area, location, seasons, bad habits, main symptoms, course, degrees, examinations (routine blood test, CRP, ESR, stool routine examination, proportion of bacteria analyzing), expressions in enteroscopy, expressions out the colon, complications, and the situations of using Chinese herbs.3.We made data by Microsoft Excel and using SPSS 19.0 to do the statistics, to study the patterns of the syndrome differentiation in TCM of UC.Results:1. The frequency showed up syndrome differentiation from high to low are damp-heat in large intestine, spleen deficiency with excessive dampness, deficiency of spleen and kidney yang, liver stagnation and spleen deficiency, simultaneous occurrence of cold and heat, deficiency of yin and blood.2. The damp-heating large intestine and spleen deficiency with dampness are commonly seen among the youth and the middle aged. In addition, the most types among the elder are damp-heat in large intestine, spleen deficiency with dampness, and deficiency of spleen and kidney yang. The main types are damp-heat in large intestine and spleen deficiency with dampness between the male and female.3. There is no obviously precipitating factor in most cases. Only 28 out of 85 medical records have obviously causes. The main factor is improper or unclean diet. The ranks from high to low are improper and unclean diet, tiredness, using medicine, catching a cold, and emotion.4. All records are in activity stage in this study. Main cases are chronic recurrence. Most cases are in severe illness.The extent of disease mostly happened in half of left colon.5. Occult blood, stool bacteria have a high rate in lab abnormalities. The main phenomena of intestinal mucous membrane are congestion and edema, erosion, ulcer, unclear vascular texture. The major level of activity of UC in colonoscopy is level ?.In histopathology, most common level is II. The histopathology of damp-heat in large intestine is higher than others. Others are much lower than those two types.6.The main oral herbs we used often have the effect of clearing heat, tonifying and hemostasis. The high frequently used herbsare Huanglian, Baishao, Huangqin,Danggui, Huangqi, Diyu, Baizhu, and Yiyiren.7.There are some notable differences between the syndrome differentiations in TCM and precipitating factor (P<0.05), so does histopathology (P<0.05).But there are no obviously differences in ages, genders, district, course, season, clinical type, clinical stage, clinical grading, extent of disease, main symptoms, lab examinations, expressions in enteroscopy, and the different levels (P>0.05). recurrence. Most cases are in severe illness.The extent of disease mostly happened in half of left colon.Conclusions:1.TCM syndrome type with damp-heat in large intestine syndrome and spleen deficiency with excessive dampness are more common.Clinical often will serve as the basic law for the treatment of the disease of spleen dampness.2.Large intestine damp heat syndrome and spleen deficiency with excessive dampness syndrome are often induced by improper and unclean diet. So the treatment of disease of the large intestine damp heat syndrome and spleen wet Yun certificate should be especially patient of the enjoin to pay attention to diet, living and spirit of nursing.3.Chronic recurrent type is more common to see,so we should grasp the basic pathogenesis of the disease,and pay attention to continuous and consolidation treatment,as far as possible to prevent recurrence.4.There is a possible correlation between histopathological grading and TCM syndrome types, which can provide an objective basis for the TCM syndrome differentiation of ulcerative colitis.5.The extent of the lesion was positively correlated with the severity of the disease. |
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