Clinical Study On Effect Of Electro-acupuncture In Improving The Quality Of Oocytes And Leukemia Inhibitory Factor In Follicular Fluid Of Polycystic Ovarian Syndrome Patients Under Going In Vitro Fertilization And Embryo Transfer

Objective: To investigate the effects of Electro-acupuncture in Improving the Quality of Oocytes and Leukemia Inhibitory Factor in Follicular Fluid of polycystic ovarian syndrome patients Undergoing in vitro Fertilization and Embryo Transfer.Methods: Women undergoing IVF-ET were randomly divided into two groups: the treatment group (31cases) was treated with Electro-acupuncture combined with Western medicine and the control group (31 cases) was only treated with Western medicine. To observe the clinical basic situation of treatment before two groups of patients, the clinical symptoms of integral comparison before and after the treatment two groups, to observation the comparison of based endocrine FSH, E₂, LH, T, PRL before treatment two sets of patients .When Started using the Gn ,to observe the comparison of endocrine FSH, E₂, LH .After treatment, to observe the changes of follicular membrane blood PI, RI in two groups. Amount of oocytes, rates of mature oocytes, fertilization, cleavage, high-quality embryos and pregnancy, as well as LIF level in FF were observed and compared between two groups.Results: (1) Before treatment, two groups were comparable and there was no significant difference (P > 0.05). (2) Clinical symptoms improved much in treatment group than control group (p < 0.05) and there were significant differences. (3) Before treatment, there were no significant differences form based endocrine FSH, E₂, LH, T, PRL results between two groups of patients (P > 0.05), it was comparable .(4)When using the Gn, there were no significant difference of based endocrine FSH, E₂, LH, results (P > 0.05), it was comparable. (5) Two groups of patients HCG day follicular membrane blood flow by t-test PI, RI comparison had extremely significant difference (P < 0.01). (6) The treatment group was obviously better than the control group in improving the amount of oocytes, rates of mature oocytes, fertilization, cleavage, high-quality embryos and pregnancy .The comparison had extremely significant difference(P<0.05. (7) The treatment group was obviously better than the control group in improving the LIF level in FF, The comparison had extremely significant difference(P<0.05).Conclusion: Electro-acupuncture has good effect on improving the quality of oocytes, and its mechanism may be related to the role in the hypothalamus-pituitary-ovarian axis. To promote the pituitary hormone release hormones produce certain effect. Increase pituitary hormone release to promote the sensitivity of the pituitary. Through the secretion of Follicle-Stimulating Hormone which was promoted by hypothalamic hormones to produce indirect regulatory role, the lever of LIF in follicular fluid, the amount of oocytes, rates of mature oocytes, fertilization, cleavage, high-quality embryos and pregnancy was improved.