Clinical Observation Of Curative Effect Of Jiaweishengmai Decoction On The Aged Chronic Heart Failure (Qiyin Deficiency)

Purpose: To observe the clinical curative effect of Jiaweishengmai decoction on the aged chronic heart failure (qiyin deficiency) and investigate its curative preponderance.Method: 60 patients were selected according to the diagnostic criteria and randomly divided into two groups, 30 as the experimental group and the other 30 as the control group. Both groups were treated by western medical regular therapy, while the Jiaweishengmai decoction was applied to the experimental group in addition. The treatment cycles for the two groups were both 4 weeks. The improvement statements of main clinical syndrome (cardiac functional grading), quality of life, and traditional Chinese medicine (TCM) disease score and the changes of brain natriuretic factor (BNP) were observed before and after the treatment.Result: Both groups have good improvements in cardiac functional grading and BNP after the treatment (P=0.000<0.01). There are no differences in the curative effect between the groups before and after the treatment(P=1.000>0.05,for cardiac functional grading, and P=0.548>0.05, for BNP). For the comparison of the traditional Chinese medicine disease score, the markedly effective rate , the effective rate and the total effective rate are 43.3%, 53.3% and 96.7% respectively in the experimental group, which there are significant differences comparing with the control group (P=0.000<0.01). There are significant differences in physical strength part, social relations part, emotional effect part and total score of quality of life in the experimental group before and after the treatment (P=0.000<0.001, respectively), and no statistical difference was found in economic effect part; The improved grades of all the parts in the experimental group are better than those in the control group (P=0.000<0.001, respectively). Conclusion: Jiaweishengmai decoction is an excellent effective prescription for the clinical treatment of the aged chronic heart failure (qiyin deficiency). This prescription can not only relieve the syndrome such as choking sensation in chest by nourishing qi and yin and benefiting heart and spleen, but also improve other clinical syndromes, mental state and quality of life, which means that it is worth using widely in clinic.