Effect Of Sijunzi Decoction And Enteral Nutrition On Thyroid Hormone And Nutrition Function In Critical Patients With Spleen Deficiency Syndrome

ObjectiveTO observe the effect of Si-Jun-Zi Decoction and enteral nutrition on Thyroid hormone and nutrition function in Critical patients with Spleen Deficiency Syndrome.Through detecting the patients'level of thyroid hormones and changing nutrition indicators in peripheralblood, estimate whether the Si-Jun-Zi Decoction is good for the Critical patients with Spleen Deficiency Syndrome on Thyroid hormone and nutrition.MethodsIn this prospective, sing-blinded,controlled study, fourty-six patients who are moved in my courtyard ICU with critical disease form January 2010 to March 2011 according to 1:1 proportion are divided into the control group and the study team stochastically that male are 25 examples, female are 21 examples, aged 28-80 years old. The control group and the study team moves in the ICU24-48 hour later, when the life symptom is steady, the homeostasis tends balanced and the gutless in nutrition contraindication starts the enteral nutrition, at the same time treats the group to pour into Si-Jun-Zi Decoction 100ml twice by the stomach tube, the treatment courses 7 days. Observing the two groups, measure the thyroid hormone (TSH,TT3,TT4,FT3,FT4) in the circumference venous blood and the change of Albumin (ALB), Prealbumin (PA), hemoglobin(HG), Transferrin(TF), lymphocyte(LYM)in the day before nutritional support and the seventh day of enteral nutrition. Record the common gastro-intestinal tract complication which in the research period, two group of patients intestines the nutrition does not endure (stomach zhu to keep, vomit, to attract, distension of the abdomen, diarrhea by mistake). The measurement material express by x±s, the group comparing uses T test, the numerical variable data uses rank sum test and the correlation uses linear correlation and regression analyse. P<0.05 has statistics significance. All statistics use the SPSS13.0 statistics software to carry on.Resultthe treatment group 23 examples, the control group 23 examples. Before the research, treats the group and control group's sex constitution compares, the age, APACHEⅡTarget difference have non-statistics significances.From the treatment group and the control group, the thyroid hormone (TSH,TT3,TT4,FT3,FT4) with the circumference venous blood and the statistics of Albumin (ALB), Prealbumin (PA), hemoglobin (HG), Transferrin (TF), lymphocyte(LYM) have no obvious differences in the day before nutritional support.7 days after the treatment, the FT3,TT3,PA,TF,LYM of the study team and treatment group have significantly promotion, but the statistics of the trentment group is obviously higher than the control group's (P<0.05). Curative treatment in western and chinese medicine practitioners groups are superior to the anxiety-provoking. The rate of gastrointestinal complications (stomach zhu keeps, vomit, to attract, distension of the abdomen, diarrhea the formation rate treatment group to be lower than the control group by mistake)that enternal nutrition intolerant in treatment group is less than in matched group.ConclusionSi-Jun-Zi Decoction auxiliary intestines the nutrition support can further improve thyroid gland function in Critical patients with Spleen Deficiency Syndrome, improve nutrition indicators and optimize the effectiveness of nutrition support.