Clinical Observation Of Using Poria Sini Soap To Cure The Type Of Deficiency Of Both Yin And Yang But Yang More Of Type 2 Diabetes Patients.

Purpose:This topic was to observe the clinical efficacy and safety and to explore its possible mechanism of using Poria sini soap to cure the type of deficiency of both Yin and Yang but yang more of type 2 diabetes patients.Method:Adopt prospective randomized controlled method, randomly divided 60 cases ofthe type of deficiency of both Yin and Yang but yang more of type 2 diabetes patients meet the diagnostic criteria and inclusion criteria into 30 patients were traditional Chinese medicine and the contrast group of 30 patients. in the treatment of type 2 diabetes, the control group would inject insulin of youmile (before breakfast and dinner each time) which the group of TCM adding Poria sini soap on basic of it. Two weeks for a course of treatment and after 2 courses, the two sets of signs and symptoms before treatment after a score and 2 and the main laboratory test results were compared and analyzed statistically.Result:At the total efficiency of curative effect of TCM symptoms, the group of TCM after a course was 90%,96.7% after 2 courses, compared to the control group after a course was 60.0%,76.7% after 2 courses.The group of TCM, in improving the symptoms of a course and after 2 courses were significantly better than the control group, there were significant differences between the two (P<0.05). The total effective aspects of Western medicine, The group of TCM and the control group no significant difference (P> 0.05), However, at the number of cases markedly, the medicine after a course of treatment was significantly better than the control group, no significant difference after 2 courses. Contract with Glycemic control after 1 course of treatment, lipid control and insulin dosage after a course of treatment and 2 course of treatment, between the two groups, The group of TCM were better than the control group as all P<0.05. There were no significant difference between the two groups in glycemic control after 2courses, as P>0.05.Conclusion:Poria Sini curing soap partial Yang deficiency of yin and yang deficiency type 2 diabetes is safe and effective. Poria sini soap's efficacy in clinical symptoms, reducing fasting and postprandial blood glucose (after 1 course), and lipids and insulin dosage (after lcourse and 2) is superior to the simple use of western medicine, with other indicators Almost equal. This effect may be related to increased insulin activity, suppress appetite and intestinal absorption of glucose and fat, influence glucose and lipid metabolism pathway, increased energy consumption, regulate activity and expression of PPARY and improve insulin resistance, insulin secretion and promoting anti-islet B cells, Anti-oxidative stress and anti-inflammatory, lipid-lowering and anti-atherosclerosis, inhibit platelet aggregation and other effects.