The Clinical Investigation On The Chronic Kidney Disease In Treating With The Methods Of Qingrejiedu

Objective:Qingrejiedu methods (QM)is one effective prescription to treat mesangial proliferative Chronic kidney disease (CKD) by my advisor based on tens of years clinical experience.The study indicated that pathogenesis of the CKD is characterized by the deficiency of ben and excess of biao, spleen and kidney deficiency of qi-yin for the ben, dampness, heat, toxin and blood stasis for the biao, so establishing nutriting yin and activating blood, cooling blood and detoxifying, clearing heat and dampness,enhance the function of spleen and kidney. Pre-clinical research indicated that QM be effective in alleviating clinical symptoms and signs, improving physical and chemical indicators. The purpose of this study through clinical observation is to evaluate objectively the QM therapeutic effect of curing CKD and to explore its mechanism. Methods:We divice 60 paitients of CKD into QM group and contrast group (Dai Wen) at randiom.Each group has 30 patients,which are treated by the same methods of modern medicime,such as resting, low salt and appropriate high-quality low-protein diet,descending blood pressure,premoting urination and giving immunosuppressive agents etc.In the same time QM capscule is given to the CDK group while Dai Wen to the controls. The two groups are one course of treatment for four weeks, continuous medication after two treatments. In the two groups,the clinical symptoms and signs, the nature of urine albumen, the station of 24 hours urine albumen,urine red blood cell count, and the change of lipids, serum creatinine, blood urea nitrogen, plasma protein and liver function before and after treatment are observed respec tively. Results:From the results of clinical research, we can see that CKD can not only alleviate symptoms and signs of the patients effectively, but also descend albuminuria and lipid,and improve plasma protein,and control hematuria,and regulate immune, and improve hypercoagulable state, and alleviate the pathological changes of renal tissue,and protect the renal function of the patients dramatically. The total efficiency is 67%, which is better than the control group significantly.The long-term oral can consolidate the efficacy of the treatment process without any adverse reactions. Conclusion:According to the results,we can conclude that QM is an efficient recipe for the insuffciency syndrome of qi-yin of spleen and kidney with wet, heat, toxic and blood congestion of CKD by delaying the progress of glomerular sclerosis,protecting the renal function,descending abluminuria, alleviating symptoms and improving life quality of the patients effectively. The therapeutic mechanicsm may have much to do with the regulation and enhanced immune function, improve glomerular filtration rate, slow down the progress of glomerular sclerosis, increased renal blood flow, improve renal hypercoagulable state related to.