Risk Factors Of The Urinary Stone Disease Concurrent Infection And The Analysis Of The Result Of The Bacteriological Examination

ObjectiveTo provide further reference for clinical therapy by finding out the risk factors contributing to urinary stone disease concurrent infection, examining the structure of the microbial population and the susceptible rate of drugs, as well as guiding the application of antibiotics during the perioperative period.MethodsRetrospective analysis of 806 cases of urinary stone disease is conducted; Incidence rate and correlated risk factors are calculated; Distinction of various factors contributing to urinary stone disease concurrent infection is studied and analyzed byχ2; Bacterial spectrum and susceptible rate of drugs are analyzed.Results178 cases of bacterium are detected out of 806 urinary samples, with the positive rate being 22.08%.Byx2, statistical significance is found between urinary stone disease concurrent infection and such factors as sex, age, multi-site stone, staghom calculus and whether there exists obstruction instead of factors like smoking, drinking, and ethnic differences. Female, advanced age, multi-site stone, obstruction and staghom calculus are risk factors. Out of the 178 stocks of pathogenic bacteria, G negative bacteria account for 93.26%, G positive bacteria 4.49%, eumycete 2.25%. Antibiotic susceptible rate shows that Imipenem is the most sensitive, being 90.8%, followed by Piperacillin Sodiumand/Tazobactam Sodium, being 71.3% and Amikacin being 69%. Escherichia coli is relatively more sensitive to Imipenem, Amikacin and dantafur; klebsiella spp is resistant to Ampicillin but most sensitive to Imipenem; Proteus mirabilis is relatively sensitive to all medication but dantafur; Pseudomonas aeruginosa is sensitive to Piperacillin Sodiumand/Tazobactam Sodium and ciprofloxacin; Statistics show that sensitiveness rate of ciprofloxacin and levofloxacin reaches 30% on the average.ConclusionSuch factors as female, advanced age, multi-site stone,staghom calculus and whether there exists obstruction are risk factors; Pathogenic bacteria are mostly G negative bacteria; Amikacin, and Piperacillin Sodium/Tazobactam Sodium can be taken as first choice for the high sensitiveness; Quinolone is not recommended as the resistance of this kind seems to be going up.