A Cluster Analysis Of Traditional Chinese Medicine Syndrome Of Chronic Heart Failure

ObjectivesTo investigate the main clinical characteristics of syndromes in TCM in patients with Chronic Heart Failure Syndrome, and to explore the" Heart and Spleen-related theory" in the clinical syndrome of heart failure, and to provide the basis for the decision of Diagnosis and Treatment.MethodsFirst, the questionnaire to collect the clinical symptoms in Chronic Heart Failure was established. Then, patients who met the inclusion criteria from the Heart Center of Guangdong Hospital of TCM and the Cardiology department of General Hospital of Guangzhou Military Region were surveyed, and their information were collected for this cross-sectional survey. Upon completion of the clinical data collection, EpiData3.0 and SPSS13.0 software database was established to record, manage, and statistiacally analyze the data.ResultThose symptoms of dyspnea, fatigue, weakness, chest pain, reduction of food intake, insomnia, pale tongue, dark tongue, white tongue and tongue coated appears≧50% among the 333 cases of patients with chronic heart failure syndromes in this cross-sectional survey of information. Cluster analysis of 273 cases of acute exacerbation of chronic heart failure patients gather 2 categories:the type of" Qi deficiency and blood stasis with water stagnation and the type of" Yang deficiency and blood stasis with water stagnation (with phlegm stagnation)". Cluster analysis of 60 cases in remission gather two categories:the type of "Yang and Qi deficiency with blood stasis" and the type of" Qi and Yin (blood) deficiency with blood stasis". ConclusionBasic pathogenesis of chronic heart failure characteristics can be summarized as "heart and spleen deficiency, phlegm and blood stasis block".The pathogenesis of Chronic heart failure syndromes can be grouped into two size:the difeciency of the Qi (Yang), on the other hand, phlegm, blood stasis blood and water stagnation. The rule of the syndrome of chronic heart failure was preliminary revealed in this study combined with literature research and clinical findings before. Under the present conditions, carrying out studies of multi-center, large sample size on chronic heart failure syndromes is of certain significance.