Study Of Buzhongyiqi Tang Comparation Between Prescription And Syndrome

Buzhongyiqi tang was created by Lin Dongyuan who was a famous doctor in Jin and Yuan Dynasties, it is composed of eight herbs including Huangqi, Renshen, Gancao, Baizhu, Danggui, Chenpi, Shengma, Chaihu, which can replenish qi to invigorate spleen and treat deficiency of the spleen-stomach and fever caused by deficiency of spleen qi and sinking of qi.Collected Buzhongyiqi tang 217 modern clinic cases from 1990 to 2008, the patients' information including symptoms and signs frequency and dosage of certain herbs, added herbs are all statistically analyzed, and adopt the golden section as division point, k-mean cluster analysis, association rule to analysis for getting relation of comparation between prescription and syndrome.The result indicates that:the cores symptoms of the prescription are poor appetite, lassitude, sallow complexion, depression, pale tongue with white coating and threaty pulse. The main symptoms are shortness of breath, the feeling of sinking and distention on the lower lumbus and abdomen, sloppy stools, dizziness. So they are mainly caused by deficiency of spleen qi and sinking of qi and the original of Buzhongyiqi tang are the core ingredients of the 217 prescriptions.The result also shows that the dosages of replenishing qi herbs are heavier than those of elevating yang herbs, which indicate that their functions are mainly replenishing qi to invigorate spleen. The core symptoms reflect symptoms of everywhere of body, thus the pathogenesis of the prescription is deficiency of spleenic qi. Meanwhile the dosages of category one and four have Slightly changed according to their main symptoms of them, which is caused by Disorder of the spleen's ascending function.Aassociation rule analysis shows that confidence between core symptoms and the core herbs of Buzhongyiqi tang is all transcend 61.8%, so both the core symptoms and the core herbs have relationship.By discussing comparation between prescription and syndrome making the relation of both prescription and syndrome more clear,objective and accurate, which can supply related information for further standardization of research and guilding clinical practice.