| Objective To observe the clinical curative effect of Sao Xuan Ling on treating psoriasis vulgaris(wind-heat type)and the influence of IL-6 in the serum of the psoriasis vulgar is patience.Providing a better curative effect,more convinient and no toxic and side effect preparation for the clinics.Methods To observe the clinical curative effect to 93 psoriatic vulgaris,including 54 men and 39 women.Setting up two groups in random,50 cases in treatment group which have oral administration of Sao Xuan Ling condensed pills,43 cases in comparison group which have oral administration Fu Fang Qing Dai capsule,give two curative time's treatment.Both of them applied Vaseline for external application.Detecting IL-6 level by RIA method in psoriatic serum and comparing in pretherapy with post-treatment.Results 1.The total efficency rate in treatment group is 92.00%and in comparison group is 72.10%after eight weeks.2.The PASI scores in each symptom are diminished between the pretherapy and post-treatment,the difference is remarkable(p＜0.05),The treatment group in diminishing both the area and the degree of skin lesion is better than the comparison group,the difference is remarkable(p＜0.05).3.The level of IL-6 in psoriatic serum has no remarkable difference between the treatment group and the comparison group before treatment(p＞0.05),and it has remarkable difference after treatment(p＜0.05).Conclusion 1.Sao Xuan Ling has good effect in improving the erythema and infiltration scales,relieving the degree and area of the lesion.This preparation can adjust immunity and relieve inflammatory reaction,from which reveal partial mechanism of action of this medicine to treat the psoriasis,provided the scientific basis for this medicine clinical promoted application.2.Sao Xuan Ling has good effect on controlling the serum IL-6 of psoriatic vulgaris.
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