Clinical Study On Treatment Of Polycystic Ovary Syndrome With Bu-Shen-Yang-Jing Decoction

Objective: To investigate the efficacy and mechanism of the Bu-Shen-Yang-Jing Decoction(BSYJD) in treating patients with polycystic ovarian syndrome (PCOS) diagnosed as deficiency of kidney syndrome. Methods: 60 patients with PCOS diagnosed deficiency of kidney syndrome were divided into two groups randomly. BSYJD was given to the treatment group including 30 patients. At the same time Ba-Zhen-Yi-Mu Granule was given to the control group including 30 patients. After 1 course of treatment, observe the changes of the syndrome of Traditional Chinese Medicine(TCM), serum hormone levels such as FSH,LH,PRL,E₂,T,INS,Basic Body Temperature(BBT) and the Ovarian volume. Results: The total effective rate is 86.67%, the ovulation rate is 73.33%, and the pregnant rate is 60.00% in the treatment group. Those rates are 60.00%,46.67%and 20.00% in the control group respectively. There are significant differences between two groups (P<0.05). The total effective rates of the syndrome of TCM are 90.00% in the treatment group,and 63.33% in the control group.There is significant differences between two groups(P<0.05).There are significant differences between two groups in improving the symptoms of TCM(P<0.05).There are significant differences between two groups in tereating different diseases of TCM(P<0.05).In the treatment group ,there is no relationship between age and effect(P>0.05), and there is no relationship between course of disease and effect either(P>0.05).BSYJD can obviously decrease the levels of LH,T,PRL,INS, increase the levels of FSH,E₂, shrink the ovarian volume, and improve the polycystic change of the ovary. Conclusion: Deficiency of kidney-Jing is the basic pathogenesis in PCOS. BSYJD is an effective medicine in the treatment on PCOS with deficiency of kidney-Jing syndrome. BSYJD can work through a variety of ways to remedy PCOS such as adjusting the abnormality of Hypothalamus-Pituitary-Ovarian aixs, improving IR,et al.