A Preliminary Study Of The Clinical Application By DSCT In Left Ventricular Function

Objective:1.To evaluate the diagnostic value of cardiac DSCT in comparison with echocardiography(ECHO) on left ventricular function.2.To investigate the relation between coronary artery disease and myocardial ischemia,left ventricular function damage by comparing coronary artery stenosis and left ventricular function measurements with coronary artery disease and clinical information.3.Observation of relationship between myocardial bridge and left ventricular regional function. Material and method:DSCT and ECHO examinations were performed on 29 healthy volunteers(normal group) and 95 cardiovascular disease patients(lesions group) within 72 hours,compared left ventricular function measurements obtained by two exams;DSCT and CAG findings were compared for the assessment of detection in coronary artery stenosis;coronary disease patient coronary artery lesion and LVMM, LVEF,LVSV carry on statistics analysis and with the clinical material comparison,to investigate the association of coronary lesion with the left ventricular function; Assessment of MB patients myocardial bridging the degree of stenosis,length and myocardial bridge plaque distribution of the merger,the extent of myocardial bridge stenosis and left ventricular regional function relationship.Results:1.LVEDV,LVESV, LVSV,IVST-ED,LVPWT-ED,LVEVd,IVST motility yielded high degree of correlation(r=0.939/0.847/0.912/0.866/0.932/0.973/0.781) in normal group;LVEF, LVFS,LVPWT movement of middle-value-related(r=0.684/0.643/0.607).2.in Lesions group,LVEDV,LVESV,LVSV,IVST-ED,LVPWT-ED,IVST movement degrees, LVPWT movement,LVEVd yielded high degree of correlation(r=0.963/0.977/0.831/ 0.862/0.857/0.802/0.854/0.938/0.812),LVEF,LVFS value relevance of the middle (r=0.607/0.638).2 Normal group of LVEF,LVSV,LVFS were more than the lesions group,LVMM less than lesions group,there is significant difference in LVMM, LVSV(P＜0.05),LVFS,LVEF was no significant difference(P＞0.05).3.32 patients with coronary heart disease exam DSCT and CAG,two exams diagnosed coronary artery stenosis without significant difference(P＞0.05).The number of coronary artery stenosis,stenosis with clinical confirmed the incidence of myocardial ischemia have significant difference(P＜0.05).LVMM,LVEF,LVSV changes were significant statistically when the number of involved coronary arteries were different(P＜0.05), LVMM significant difference between groups(P＜0.05).LVEF,LVSV in three lesion group and single-vessel disease,double vessel disease there is significant difference between groups(P＜0.05).Single-vessel disease,double vessel disease was no significant difference between groups(P＞0.05).The extent of coronary artery disease and LVEF,SV mild stenosis group and moderate stenosis,severe stenosis group significant difference between(P＜0.05),mild stenosis group arid the moderate stenosis group had no significant difference(P＞0.05).4.Single-vessel disease MM, LVEF and SV significant difference between groups(F=39.52/16.74/17.30,P＜0.05); LAD lesions were the largest loss of left ventricular function;.LAD stenosis and ventricular septal significant difference between changes(P＜0.05).5.Lesions group were detected MB 24 cases(25.26%,24/95) Mural coronary artery 30,combined 17 cases of coronary artery plaque(54.8%),MB did not appear above of coronary artery plaque.The extent of coronary artery wall stress compared with the thickness of myocardial bridge the differences statistically(P＜0.05);mural coronary artery stenosis more severe left ventricular damage,the more obvious movement. Conclusion:1.DSCT coronary angiography can be the method to check a number of indicators,and compared with the ECHO in evaluation of left ventricular function.it was highly accuracy.2.The extent of coronary artery stenosis,vascular disease and myocardial ischemia and left ventricular regional function have a certain relationship. 3.DSCT visual display cardiac muscle bridge and with left ventricle cardiac muscle thickness,movement change relations.