Study Of Analyzing The Chinese Medicine Prescription Of Chronic Glomerulonephritis Of Famous Physicians Of TCM Professor Huang And Famous Physicians Of TCM Professor Zhang With Data Mining

Objective:Analyzed TCM Prescription of Chronic Glomerulonephritis of Famous Physicians of TCM Professor Huang And Famous Physicians of TCM Professor of TCM Zhang with the platform of prescription Data mining(DM) technique to learn and inherit their experiences and knowledge on chronic glomerulonephritis.Provided a new approach for the analysis of Chinese medicine prescriptions and the study of Prescription.Methods:Inputed separately the 100 TCM Presciption of Chronic Glomerulonephritis of Famous Physicians of TCM Professor Huang and Famous Physicians of TCM Professor Zhang into the database of prescription analysis.Mined the data of composition of Prescriptions of TCM,property of herbs,flavor of herbs, flavor of herbs,meridian distribution,type of TCM Prescriptions and action of TCM Prescriptions then generalized the results,summed up the common experience of the above 2 experts and the individual experience of each them on the clinical therapy of the Chronic Glomerulonephritis and explored the similarities and differences of the above results and monographs of the 2 experts.Results:1 The individual experience of 2 experts on TCM Prescriptions of Chronic Glomerulonephritis of the Similarities and differences between the results of prescription Data mining(DM) and contributions of the 2 experts.1.1 The excavation and analysis of Chinese Medicine Prescription of Chronic Glomerulonephritis Professor Huang.1.1.1 Composition of TCM Prescriptions:the herbs most frequently used are cornus officinalis,ganoderma lucidum,astragalus salvia miltiorrhiza, eucommia,adenophora,agastache,cuttlebone,pachyman,cassia,dodder,polygonum multiflorum,icariin,costunolide,cortex moutan,pyrrosia,cirsium setosum,cirisium japonicum,licorice,paris polyphylla.1.1.2 Distribution of property of medicinal herbs:eveness,light warm nature,warmnature,coolnature,lightcoldnature,coldnature.1.1.3 Distribution of flavor of herbs:sweet,bitter,acid.1.1.4 Meridian distribution:in terms of meridian distribution,the sequence according to The proportion of frequency is liver,kidney,lung,spleen,heart, stomach,largeintestine,pericardium,bladder,gallbladder,smallintestine,tri ple energizer.1.1.5 Type of TCM Prescriptions:(1) Root deficiency:qi deficiency;yin deficiency,and yang deficiency,blood deficiency.(2) Branch excess:excessive fluid together with phlegm dampness;blood-stasis;damp-heat;phlegm-heat stagnation;excess heat syndrome;blood heat;Qi stagnation.1.1.6 Action of TCM Prescriptions:The main action is reinforcing deficiency. qi-tonifying,diuresis and decreasing tumescence,blood-tonifying,reducing damp and heat,nourishing Yin,invigorating the kidney,blood-activating and stasis-eliminating,eliminating heat-evil fire from the blood,promoting qi and relieving pain,clearing the lung-dissipating phlegm,surging fire and detoxication,relieving mental stress,nourishing yang,invigorating kidney.1.2 The Similarities and differences between the results of prescription Data mining(DM) and contribution of Professor Huang1.2.1 Pathogenesis:pathogenesis is Root deficiency and Branch excess,but the Root deficiency of contribution of Professor Huang is kidney and spleen deficiency,the results of prescription Data mining is liver,kidney and spleen deficiency;Branch excess of contribution is wind,cold,damp,heat,blood stagnation,the results of prescription Data mining is damp,heat,phlegm, blood stagnation and Qi stagnation.1.2.2 the Part of disease of contribution is kidney and spleen,the results of prescription Data mining is liver,kidney,spleen and lung.1.2.3 Herbs:the main Prescription of contribution of Professor Huang is Liu Wei Di Huang Tang And Si Jun Zi Tang. 1.2.4 Treatment principles:principles of contribution of Professor Huang is Tonifying body and Immunosuppression.1.3 The excavation and analysis of Chinese Medicine Prescription of Chronic Glomerulonephritis Professor Zhang1.3.1 Composition of TCM Prescriptions:the herbs most frequently used are Astragalus membranaceus,bupleurum chinensis,imperata cylindrica,rehmannia glutinosa,cirsium setosum,glycyrrhiza uralensis,poria cocos,codonopsis pilosula,cornus officinalis,atractylodes macrocephala,alisma orientalis, coptis,ophiopogon japonicus,paeonia lactiflora,rubia cordifolia,dianthus superbus,polygonum aviculare,prunus persica,angelica sinensis,dioscorea opposite.1.3.2 Distribution of property of medicinal herbs:cold nature eveness,cool nature,warm nature,light warm nature.1.3.3 Distribution of flavor of herbs:sweet,bitter,acid.1.3.4 Meridian distribution:in terms of meridian distribution,the sequence according to The proportion of frequency is liver,spleen,lung,stomach,kidney, heart,largeintestine,bladder,gallbladder,smal intestine,pericardium,triple energizer.1.3.5 Sydrome type of TCM Prescriptions:Root deficiency:yin deficiency,qi deficiency,yang deficiency,blood deficiency.Branch excess:the proportion of excessive fluid together with phlegm dampness,damp-heat,blood- heat,excess heat syndrome,blood -stasis,phlegm-heat stagnation,Qi stagnation.1.3.6 Action of TCM Prescriptions:The main action is reinforcing deficiency. diuresis and decreasing tumescence,reducing damp and heat,nourishing Yin, qi-tonifying,invigoratingspleen,surgingfireanddetoxication,blood-activati ng and stasis-eliminating,eliminating heat一evil fire from the blood, blood-tonifying,clearing the lung-dissipating phlegm.1.4 The Similarities and differences between the results of prescription Data mining(DM) and contribution of Professor Zhang.1.4.1 Pathogenesis:The Basic pathology of contribution of Professor Zang is kidney and spleen deficiency,the results of prescription Data mining is liver,kidney and spleen deficiency;Branch excess of contribution is wet,damp-heat,blood stagnation,The Basic pathology of the results of prescription Data mining is Yin deficiency,Branch excess is damp-heat,phlegm dampness,phlegm-heat,excess heat,blood stagnation and Qi stagnation. 1.4.2 the Part of disease of contribution is kidney,lung and spleen,the results of prescription Data mining is liver,kidney,spleen and lung.1.4.3 Herbs:the main Prescription of contribution of Professor Zhang is Qing Xin Lian Zi Yin,Qing Re Li Shi Tang,Hua Fen Qu Mai Tang,He Zhong Xiao Zhang Yin,Xin Fang Liu Qi Yin,Jia Wei Zhen Wu Tang,Jia Wei Di Huang Tang,Yi Qi Bu Shen Gu She Re Ji,Tao Huang Zhi Xue Tang.1.4.4 Treatment principles:principles of contribution of Professor Zhangis nourishing Yin and qi-tonifying,eliminating heat and Dampness,clearing heat from the lung,blood-activating.2.The Similar and different experience of 2 experts on treatment of Chronic Glomerulonephritis.2.1 The same points:2.1.1 Composition of TCM Prescriptions:The same herbs of TCM Prescriptions of the 2 experts are cornus officinalis,salvia miltiorrhiza,poria cocos, glycyrrhiza uralensis,cirsium setosum;in terms of the flavor of herbs,the 2 experts think that sweet,acid,bitter are the main flavor;they also think that the main meridian distribution of herbs is liver,kidney,lung,spleen.2.1.2 Sydrome type of TCM Prescriptions:Analysis of TCM Prescriptions showed that the syndrome type is deficiency and excess coexist,but deficiency is important.This recognition was consistent with physicians of past generations.2.1.3 Action of TCM Prescriptions:the main action is diuresis and decreasing tumescence,reducing damp and heat,tonifying qi,nourishing Yin,activating blood and eliminating stasiseliminating heat-evil fire from the bloodsurging fireclearing the lung-dissipating phlegm and promoting qi.2.2 The different point:2.2.1 Distribution of property of medicinal herbs:The main property of medicinal herbs of Professor Huang is eveness and warm nature,and Professor Zhang is eveness and cold nature.2.2.2 Pathogenesis:The main pathogenesis of the DM results of TCM Prescriptions of Professor Huang is Qi-deficiency,that of Professor Zhang is Yin-deficiency.2.2.3 Action of TCM Prescriptions:The main action of TCM Prescriptions of Professor Huang is tonifying qi and nourishing spleen,and The main action of TCM Prescriptions of Professor Zhang is tonifying yin. Conclusion:Through the analysis of TCM Prescriptions of the 2 experts,we can learn and inherit their experiences and knowledge on chronic glomerulonephritis and learn the similarities and differences of the above results and monographs of the 2 experts.Meanwhile it was helpful to inherite and develop the academic experience of famous physicians of TCM.Based on the database of prescription analysis,TCM Prescriptions were qualitation and quantitated,It was feasible for the study of TCM Prescriptions.The results of the platform of prescription Data mining were not in full compliance with the experiences of the two famous physicisans of TCM.The knowledge base and analysis method need be improved.