Research Analysis Of Professor Shao Zhaodi's Experiences On Treating Chronic Glomerulonephritis

This subject relies on the "11th Five-Year" National Science and Technology Support Program——"Exploration on transfer the experience and academic thought of the aged famous doctor of TCM (Traditional Chinese Medicine)". Through the clinical practice with Professor Shao Zhaodi, the author collects and organizes her clinical material of diagnosing and treating in order to research Professor Shao's clinical experience and academic thought toward the treatment of Chronic Glomerulonephritis (CGN), offer clinical references for treatment of CGN with TCM, and establish the theoretical foundation for inheriting the famous old doctor's experience in combination with this research.Chronic Glomerulonephritis, abbreviated to Chronic nephritis, refers to the proteinuria, hematuria, edema, high blood pressure as the main clinical manifestation, more than a year, different onset of ways, protracted, slow progressed, and eventually will be developed to the chronic renal failure in a Groups of glomerular disease.The topics are described in chronic glomerulonephritis with normal function.There is no record of "Chronic glomerulonephritis" in TCM, but it could be classified as "edema","hematuria","lumbago","Asthenic" and so on, based on its clinical manifestations. Professor Shao considers the deficiency of zangfu-organs are the basis of this disease, invasion by exogenous is a major incentive and moisture,damp heat,blood stasis are the main pathological products. CGN with a long an protracted course is expressed as a complex characteristics of the pathogenesis, inclusions of exterior and interior, intricate cold and heat, coexistence of deficiency and excess, but the deficiency of zangfu-organs is the key to disease pathogenesis.Clinical differential diagnosis often is divided into four types:deficiency of the lung and kidney,deficiency of Qi and Yin, deficiency of Yin of the liver and kidney,deficiency of Yang of the spleen and kidney. The one who is deficiency of the lung and kidney should tonify the lung and kidney and give Yu Ping Feng San and Liu Wei Di Huang Pill. The one who is deficiency of Qi and Yin should reinfore QI and nourish Yin and give the addition and subtraction of Shen Qi Di Huang Tang. The one of deficiency of Yin of the liver and kidney should nourish Yin of liver and kidney and give Yiguan Jian pill. The one of deficiency of Yang of the spleen and kidney should invigorate yang of the spleen and kidney and give the addition and subtraction of ji-Sheng Shen Qi Pills.Based on the whole dialectic, Professor Shao has a progressive perspective for the clinical manifestations of chronic nephritis, such as proteinuria, hematuria, edema, high blood pressure. The fundamental pathogenesis of proteinuria is the spleen and kidney deficiency can not astringent essence, and give a therapeutic rule of tonifying spleen and kidney and convergence astringent,with shuiludihuang Decoction modified which is professor Shao self-made. professor Shao considers that the hot and humid is the major pathological factor in renal hematuria, but also a key pathological factor for lingering refractory exacerbations. In the time of the provisional certificate hematuria, professor Shao focus on the hot and humid, distinguish asthenia and sthenia. The sthenia are clearing away heat,removing damp and arresting bleeding with the addition and subtraction of xiaojiyinzi. The asthenia are nourishing Yi and cooling blood by clearing away heat with the addition and subtraction of zhibodihuangtang. Professor Shao is good to treatment based syndrome of edema, considering that edema is not always lung, spleen and kidney,butnot forgeting the liver in the pathogenesis, and that warming Yang is the common method in the treatment of edema, but having a good effect when nourishing Yin. The dialectic of chronic nephritis with hypertension identified mostly deficiency of Yin of liver and kidney, linger of heat and humidity. Based on the whole dialectical, professor Shao often uses Achyranthes bidentata, Plantago 2 taste, nourishing the liver and kidney, clearing away heat and removing damp, flating tone blood pressure.The slow progression of chronic nephritis, throughout the course of the disease process of growth and decline of the vital and the Evils, lead to the complexity of pathogenesis and symptoms of the volatility, but from the basic pathogenesis of the disease professor Shao seizes the essence of the disease and considers that the Deficiency of the zangfu-organs y is the base of incidence of this disease. Invasion of lung, hurting spleen, damaging kidney in chronic nephritis disease progressive approach to the process, the treatment based on the virtual, in particular the spleen and kidney.invasion of exogenous is the major incentive factor of this disease, wet, heat and blood stasis are the evolution of this disease in the major pathological product, because of real-induced virtual, directly or indirectly increasing deficiency of zangfu-organs, so that vital Qi and evil Qi dynamics, lingering illness refractory, therefore, professor Shao takes into account standard sthenia and emphasizes Quxie at the same time of basing on the virtual.In the clinical part of the illness in patients with chronic nephritis disease is minor or hidden, the symptoms are not noticeable, only urine abnormalities. This part of chronic nephritis patients face that there is no symptoms to argue and situation of dialectical difficult. For this part of the patient, professor Shao will be dialectical combination with the identified disease, and based on the overall dialectical, the outstanding disease differentiation.professor Shao uses drugs with Qing Ping, gongzhuan, designed flexible with the addition and subtraction, not large cold and large heat. For patients of clinical proteinuria in syndrome differentiation, on the basis of the whole professor Shao is pleased with jinyingzi and qianshi (land and water two of immortality), that the two have a function of tonifying spleen and kidney, convergence astringent. Baimaogen with Gan Han can clear away heat and cool blood to stop bleeding, Qiancao is good at promoting the blood, both cooling blood to stop bleeding, but also circulating blood to stop bleeding. The two drugs consistency cool blood to stop bleeding without leaving bruises. For the treatment of chronic nephritis, professor Shao specially emphasises on regulation during convalescence, both therapeutic and prevention, often clinical supervises patients.