Clinical Reseach Of Cases With Chronic Pelvic Inflammatory Disease Treated By No.1 Enema Prescription Of Chinese Herbs

Objective To study the clinical efficacy of curing chronic pelvic inflammatory disease with the No.1 enema prescription of Traditional Chinese Medicinal herbs created by our department,and to provide scientific foundation for its application in clinic.Methods The objects of this study were the patients from Gynecology Outpatient Wards of Guangzhou Hospital of TCM.The patients all suffered from chronic pelvic inflammatory disease due to dampness and heat accumulation.90 paitients were randomly divided into 3 groups.The treatment group received the No.1 enema prescription of traditional chinese medicinal herbs(prescription compositions:salvia miltiorrhiza and hedyotis diffusa willd each 30g,radices paeoniae rubra,rhizoma sparganii,rhizoma corydalis and radices curcumae zedoariae each 10g, cortex phellodendri 12g,common andrographis herb 20g).The control group 1 received enema by metronidazole injection and the control group 2 received the oraltreatment of rhizoma smilacis chinensis capsule.Each group went with 3 courses of treatment to study the difference of efficacy among groups,among courses,as well as between before and after the treatment.Statistical analysis was performed with SPSS 15.0.Results(1)Compared with the patient' s age and the course of disease, there were no significant difference among the treatment group,the control group 1 and the control group 2.(2)After three treatment courses,The total effective rate of the treatment group was 96.66%and the control group 1 was 60%,the control group 2 was 53.34%individually(P＜0.05). (3)After three treatment courses,the treatment group had a significant difference in the main symptom score from the two control groups(P＜0.05).The treatment group had a significant difference in the main symptom score between before and after three treatment courses(P＜0.05).However,there were no significant difference in the control group between before and after three treatment courses(P＞0.05).(4)After three treatment courses,the treatment group had a significant difference in the physical sign score from the two control groups(P＜0.05).The treatment group had a significant difference in the physical sign score between before and after three treatment courses(P＜0.05).However,there were no significant difference in the control group between before and after three treatment courses(P＞0.05).(5)After the 3 courses of treatment in the treatment group,the third treatment course had a distinctive efficacy than the first and second treatment course.There are a significant difference in the total effective rate between the third treatment course and the second treatment course(P＜0.05).And the second treatment course had a distinctive better effect than the first course(P＜0.05).The total effective rate of the third treatment course was 96.66%,and the second one was 53.33%,the first one is 46.67%.Conclusion(1) There is remarkably effective in curing chronic pelvic inflammatory disease due to dampness and heat accumulation by our department' s No.1 enema prescription of Chinese herbs.(2) Our department' s No.1 enema prescription of Chinese herbs is significantly effective in the disappearance rate of the main symptoms and physical signs of the patients of chronic pelvic inflammatory disease.(3) Our department' s No.1 enema prescription of Chinese herbs has a positive correlation between the efficacy and the treatment courses in treating chronic pelvic inflammatory disease due to dampness and heat accumulation,which means the longer the treatment courses are,the more effective it can be.