The Clinical Study On Curative Effects Of Gout With Moist Heat And With Blood Stasis Syndrome Treated By Lijietang Decoction Combined With Colchic

Objective:This study objective is to approach the clinic therapeutic effect,security and adverse effect of the Lijietang to gout,to search for a more secure and more effective treating method of Chinese Traditional Medicine,by setting up control group and comparing interclass transversally of the pretherapy and posttherapy.Methods:In this experiment,70 cases of patients with the acute gouty arthritis were selected in the research and they were divided into two groups randomly.35patients were selected as the treatment group(treated with"Lijietang" combined with Colchicine),The patients in control group(35 cases) were treated with routine therapy in Western medicine,including Colchicine,Diclofenac Sodium Enteric-Coated Sustained Release Capsules and Allopurinol Tablets.The clinical symptoms,UA,ESR,CRP,HOMA-IR, lipid(TC,TG,HDL,LDL) were measured and compared before and after treatment.Result:1,The evaluation of the curative effect:the treatment group is 100%,the control group is 96.77%,and the two groups have no statistical significant(P＞0.05)。2,The changs of guide line:1) Compared with pretherapy,the UA,ESR,CRP in the two groups in post-treatment are lower.The differences were highly significant (P＜0.01)。2) The differences of UA,HOMA-IR,TG between the treatment group and the control group were significant(P＜0.01)。3) The melioration of the marks of clinical symptoms in the treatment group is higher than control group,the differences were highly significant(P＜0.01).3,The adverse effects:In the two groups no abnormalities were found in the three routine examinations,hepatic function,renal function.In the acute gouty arthritis,5 patients had light diarrhea,4 patients had vomiting disease and 6 patients had poor appetite in the treatment goup;and in the control group,there is 7 patients had light diarrhea,6 patients had vomiting disease and 5 patients had poor appetite.In the gouty remission,2 patients had skin rash in the control group.Conclusions:The treatment group could reduce Serum uric acid,erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP),improve insulin resistance index,and improve patients' clinical symptoms.It's a effective method to treat gout with moist heat and blood stasis syndrome.