A Retrospective Analysis Of The Esophageal Carcinoma Diagnosed By Endoscopy In Gansu

Objective To investigate the clinical epidemiological characteristics of esophageal carcinoma and its trend during the past 30 years in Gansu province.Method Patients with esophageal carcinoma which were diagnosed by endoscopy and pathology from Jan 1977 to Dec 2006 were selected.The main clinical data,epidemiological, endoscopic manifestation and the pathological characteristics were studied.All datas collected were analyzed by a SPSS 10.0 software package with x~2,t test.A statistically significant difference was indicated by a P＜0.05.Results Totally 689348 patients received gastroscopy examination during the past 30 years,and 9736 patients were diagnosed as esophageal carcinoma.The overall diagnosis rate of esophageal carcinoma was 1.41%in the past 30 years.The median age of the 9736 patients with esophageal carcinoma was 60 years old,with the predominant age ranged from 50 to 69 years old.The ratio between male and female was 3.84:1,which was gradually increased with increasing of age.The constituent ratio of the upper,middle,or lower segment have not changed obviously.The proportion of esophageal adenocarcinoma(8.78%)was significantly lower than squamous cancer(91.20%),and the esophageal adenosquamous was rare(0.02%).The highest rate of detection was in Wuwei(5.07%).Conclusions The proportion of esophageal adenocarcinoma was significantly lower than squamous cancer.Esophageal adenocarcinoma occurred most frequently in the lower,but esophageal squamous cancer occurred most frequently in the middle or upper.The mean age of the esophageal cancer patients has rose over the past thirty years.Wuwei is a high-incidence area of esophageal cancer.Early prevention and control work for esophageal carcinoma in Wuwei has great significance.