Evaluation Of Narrow-band Imanging Endoscopy In The Diagnosis Of Early Esophageal Cancer

Objective To evaluate the narrow-band imaging endoscopy(NBI) in the diagnosis of early esophageal cancer.Methods 96 patients with esophageal mucosa roughness,erosion, plaque,abnormal color and indentation in conventional endoscopy and 10 cases of physical persons were erolled.The esophagus was examined by the conventional endoscopy,NBI endoscopy,NBI combinded with magnifying endoscopy and Chromoendoscopy(Lugol's iodine staining).Then we carefully observed the outline of lesions and the intrapapillary capillary loop(IPCL) and evaluated the image clarity.The biopsies underwent pathologic evaluation.The comparion between the endoscopic findings and histological results was evaluated.Results(1) The pathologic diagnosis of all the patients showed that there were 30 esophagitis,12 early esophageal carcinoma and 54 other diseases.(2)Visualization of esophageal cancer's lesions by NBI endoscopy and Chromoendoscopy were clearer than the conventional endoscopy.And there was no significant difference between NBI endoscopy and Chromoendoscopy.Visualization of IPCL by NBI combinded with magnifying endoscopy was clearer than the magnifying endoscopy.(3) 90%normal people was typeⅠ,86.7%(26/30) esophagitis was typeⅡ,and 91.7%(11/12) early esophageal carcinoma was typeⅢand typeⅣ.The difference was significant between early esophageal carcinoma and normal mucosa(X~2=20.70,P＜0.005),and between early esophageal carcinoma and esophagitis(X~2=32.48,P＜0.005).There was also a significant difference between the esophagitis and normal mucosa (X~2=26.14,P＜0.005),and between mucosal carcinoma and submucosal carcinoma.Conclusion As a novel endoscopic system,NBI is very esay to operate,and it can not only capture the optimal images of the early esophageal carcinoma's lesions,but also show the IPCL.The IPCL is closely related to the histological results.Also the IPCL can help us determine the invasion depth of the cancer.