Clinical Epidemiology Analysis Of 2627 Cases Of Esophageal Cancer

【Objective】To investigate the clinical epidemiological characteristics and the changing trend of esophageal cancer in the Cancer Hospital of Guangxi Medical University during 30 years, and to provide a reference for the prevention and treatment of esophageal cancer in this area,【Methods】 The medical records of patients with esophageal cancer were selected from the 1985-01-01 to 2014-12-31 of the affiliated Cancer Hospital of Guangxi Medical University. The clinical data of the 1 groups were treated by the time of 10 years, the clinical data of the 3 groups and all patients were statistically analyzed.【Results】 1 Clinical features:62.70% of patients with countryside, accounting for 37.30% of the town,69.66% of the Han population,27.10% of the Zhuang nationality, and the ratio of male to female was 4.34:1;the average age was 58.59, the age of onset was 51-70 years (65.21%);20.75% of patients with comorbidities;the middle part of the patients was main (59.88%); the pathological type was squamous cell carcinoma (93.19%);the most common clinical symptom was progressive dysphagia(78.19%);Comprehensive treatment was main(43.01%),while 37.50% of patients was treated with surgery.2 Development trend:the average age of esophageal cancer patients in 30 years was on the rise (P<0.05);the proportion of men to women was increasing (P<0.05);the proportion of patients with lower part of esophageal cancer and stage of Ⅲ to Ⅳ showed a ascending tendency (P<0.05);patients with comorbidities showed a upward trend in the proportion(P<0.05); patients with Comprehensive treatment showed a upward trend in the proportion(P< 0.05),while operation rate has not improved significantly (P> 0.05).3 Regional differences:The region of higher constituent ratio of patients with treatment were Guinan (38.94%) and Guidong (29.31%), followed by Guixi (20.21%) and Guizhong (8.87%) region, the lower was Guibei (2.66%) region. There were statistical differences between every region in sex ratio,average age, proportion of patients with stage of Ⅲ to Ⅳ, proportion of Zhuang nationality,and operation rate (P<0.05).[Conclusion] The incidence of esophageal cancer in Guangxi is in a older population, the Han population is main,the incidence of rural areas is higher than that of urban areas,men are significantly more than women, the middle part of the patients is main,the pathological type is squamous cell carcinoma, the clinical symptom was progressive dysphagia and patients with late, the number of patients with Comprehensive treatment increase year by year, operation rate with low. We should strengthen the region especially cancer knowledge popularization in rural areas and for high-risk groups to take cancer screening, taking prevention according to differences in every region,to improve the effect of early diagnosis and treatment.