The Study Of Tridimensional Personality Characteristics In OCD And Their First Degree Relatives

Objective: To explore the tndimensional personality characteristics of OCD and their first degree relatives. To explore the differences of the tndimensional personality characteristics of OCD and their first degree relatives. To investigated the reliability and validity of Chinese version of Clonginer's Tridimensional Personality Questionaire(TPQ). Methods: To test the reliability and construct validity of TPQ in a representative Chinese sample of 536 normal people.To investigate the test-retest reliability in 108 normal people in Sichuan Normal University. Compared the tridimensional personality characteristics of OCD(N=84) and normal control group(N=234) . Compared the tridimensional personality characteristics of OCD's first degree relatives(N=48) and normal control group(N=95). Compared the tndimensional personality characteristics of OCD(N=84) and their first degree relatives(N=48). The data were analyzed by SPSS 12.0 (Statistical Package for the Social Science) on computer, using F test, idependent-samples T test, reliability analysis and correlate satistical ways.Results:1. The Cronbach a coefficient of the Chinese version of TPQ is 0.859. The construct validity is good. The test-retest reliability correlation coefficient ofthe three dimensions are NS: 0.829, HA: 0.850, RD: 0.683.2. The NS1, RD3 scores of OCD (3.62, 6.10) are lower than the normal control group( 4.12, 7.10), P<0.05. The NS4, HA, HA1, HA2, HA3, HA4 scores of OCD (4.64 ,21.51, 6.35, 4.85, 3.91, 6.42) are higher than the normal control group(3.94, 13.15, 3.52, 3.41, 2.71, 3.51 ), P<0.05. The TPQ scores pattern of OCD is high in HA scores and low in NS and RD scores. The HA dimensional dysfunction support the 5-HT hypothesis of OCD.3. The HA, HA1, HA2 scores of OCD's first degree relatives( 16.38, 4.58 , 4.35) are higher than the normal control group(13.57, 3.53, 3.64), p<0.05. The TPQ scores pattern of OCD's first degree relatives is high in HA scores and low in NS and RD scores.4. The NS, HA, NS2, NS3, NS4, HA1, HA4 scores of OCD (15.05, 21.51, 3.29, 3.50, 4.64, 6.35, 6.42) are higher than the OCD's first degree relatives(11.48,16.38,2.46,2.42,3.29,4.58,4.13), P<0.05. The RD1 scores of OCD (3.60) are higher than the OCD's first degree relatives(4.27 ), P<0.05. The similarity of the OCD's and their first degree relatives' TPQ results surpport that OCD was heritage in some extent.5. There are positive relatives between HA dimension and it's four factors scores of OCD and Y-BOCS and HAMA scores of OCD。 The correlation coefficient of HA, HA1, HA2, HA3, HA4 with the Y-BOCS scores and HAMA scores are 0.530, 0.513, 0.371, 0.421, 0.382 and 0.502,0.511, 0.384, 0.412, 0.304 (P<0.05). Conclusion:1. The Chinese version of TPQ has good reliability and validity.2. The TPQ scores pattern of OCD is high in HA scores and low in NS and RD scores. The tridimensional personality characteristics of OCD are nearly always fearful and anticipating harm, extremely pessimistic and inhibited by unfamiliar situations, strangers, and minor risks, highly fatigable so that activities must be limited to minimize effort required, resists attempts to modify familiar routines, dependent on emotioanl supports. The research support the 5-HT hypothesis of OCD.3. The TPQ scores pattern of the OCD's first degree relatives is high in HA scores and low in NS and RD scores.The tridimensional personality characteristics of OCD's first degree relatives is noticeably inhibited and tense even under ordinary circumstances, frequent worrying far in advance about minor difficulties, moderately pessimistic and negativistic.4. The TPQ scores pattern and tridimensional personality characteristics of OCD is similar to their first degree relatives. It hinted that the tridimensional personality characteristics of OCD was heritage in some extent.5. There are positive correlation between HA dimension and it's four factors scores of OCD and the severity of obsessive-compulsive symptoms and anxienty in OCD. It hinted that obsessive-compulsive and anxiety were similar in the 5-HT dysfunction.