Randomized, Controlled, And Blinded Studies On The Clinical Symptoms And Quality Of Life Of Patients With Functional Constipation

Objective:The objective of this study was to observe and evaluate the therapeutic effect and improvement living quality of "Ji Chuan Bai He Shu" in patients with functional constipation by using randomized, controlled and sing-blind approaches,,thus improving the living quality of these patients and helping save the social resources.Methods:180patients with typical FC who meet the entry criterion in coloproctology.Then a randomized, controlled, single-blind study method was used under the support of statistical software. These patients were randomly divided into control group A、blank groupB and study group C.Patients in group A were administered with "Ji Chuan Bai He Shu" exercise therapy intervention plus oral placebo.Patients in group B were given oral polyethylene glycol4000Powder,while patients in group C(n=60) were given oral placebo.All these patients were under observation for one month and follow up for3months. For A, B, C three groups of safety, efficacy of a prospective clinical observations and records related to the evaluation (score constipation efficacy, safety evaluation, constipation efficacy index, SF-36quality of life questionnaire score, etc.) application SPSS17.0statistical software for analysis and statistics, with P<0.05as statistically significant.Res luts:There was statistical difference in the total score of clinical symptoms after1week’s,2weeks’,3weeks’or4weeks’treatment and in SF-36life quality score after3months’treatment in groups A and B; There was statistical difference in the total score of clinical symptoms after1week’s,2weeks’,3weeks’or4weeks’treatment,but no statistical difference in SF-36life quality score after3months’treatment in group C; In groups A and B,no significant difference was observed(P>0.05) upon the total score of clinical symptoms of the patients and safety evaluation etc. after the testing treatments.However, a significant difference (P>0.05)was observed upon SF-36life quality score of the patients; There was statistical difference in both total score of clinical symptoms and SF-36life quality score between group C and group A,B,but no significant difference (P>0.05) upon the safety evaluation after the testing treatments.Conclusion:"Ji Chuan Bai He Shu"and polyethylene glycol4000powder both could help relieve the symtoms of FC and enhance the living quality of the FC patients. However,"JiChuan Bai He Shu"worked better in improving living quality of the FC patients than polyethylene glycol4000powder. Meanwhile, in the placebo group had a certain effect through basic conditioning, but the effect is not obvious. Therefore, as a professional Chinese medical therapy of Chinese physical and breathing exercises,"Ji Chuan Bai He Shu"was proved to be the better one that could regulate the gastrointestinal tract and give out a more targeted therapy and precautions in FC treatment, thus achieving a higher clinical value and promotional value.