The Study On Inhalational Anesthesia With Enflurane In Dogs

Effects of enflurane on respiratory, circulatory, cardiac and encephalic functionswere investigated in healthy minitype dogs undergoing intermittent positive pressureventilation (IPPV) and operation experiments, and monitored in a non-invasive way withmultifunctional physiologic grapher SJ-42, Datex respiratory monitor and circulatorymonitor.The best effects of anesthesia was reached when the end-tidal enfluraneconcentration was l.6%, i.e. 0.7MAC by checking clinical reflexes and algesthesia.Induction and recovery from anesthesia were fast and stable.Respiratory monitor showed that although enflurane had repressive effects onrespiratory system, the dogs were guaranteed smooth respiration and abundant oxygenwith application of controlled mechanical ventilation(CMV) and side streamspirometry(SSS).Circulatory monitor and electrocardiogram(ECG) showed that body temperaturesand heart rates reduced against time of inhalation and did not recovery after ceasing ofinhalation;rhythms of hearts were stable. Blood pressure decreased against enfluraneconcentrations. It was concluded that enflurane had repressive effects on circulatorysystem. Pulse oximetry(SpO₂) had no obvious changes during anesthesia.Electroencephalogram(EEG) showed that during enflurane anesthesia EEGtransformed from high frequency, low amplitude and fast rhythm to low frequency, highamplitude and slow rhythm, and to the reverse during recovery. EEG also showed thatinduction and recovery from enflurane anesthesia were fast.It was concluded that in minitype dogs, anesthesia with enflurane has obtainedsatisfying effects, fast induction and recovery, convenient depth control and broad safetyrange of anesthesia. Noninvasive monitoring techniques play an important role onreduction of accidents of anesthesia and guarantee of operation security.This study settled an inhalational anesthesia model for minitype dogs, which was thefirst in China, and grounded toward popularization and application of inhalationalanesthesia in veterinary clinic.Ruiping Hou Major:Veterinary medicineSupervisor: Prof. Hongbin Wang...