Clinical Research On Menopausal Insomnia Treatment With Jin Three Needle Therapy

ObjectiveThis research intends to evaluate the effectiveness of treating Menopausal insomnia with Jin three needle therapy. We used randomized controlled clinical trial to compare Jin three needle therapy and Estazolam Tablet’s effectiveness of sleeping disorders and depression. We hope to propose an optimization solution for Menopausal insomnia.MethodsResearch objects are90patients who were diagnosed as Menopausal insomnia in the clinic I work for and the First Affiliated Hospital of Guangzhou University of TCM’s acupuncture department from February2013to February2014. The patients who met inclusion standards were randomly divided into the treatment group and the control group according to1:1comparison principle, both45cases. The treatment group is treated by Jin three needle therapy. We used electro-acupuncture on Melancholy three needle points and Stabilizing shen points at both sides. Treatments were done3times a week on Monday, Wednesday and Friday. The control group was treated by Estazolam tablet lmg daily bedtime.4weeks for a course of treatment. Records were made before,1week and4week after the treatment. We evaluated their improvement and the clinical efficacy according to The Pittsburgh Sleep Quality Index (PSQI), Hamilton’s depression scale (HAMD), and Unified international sleep efficiency value. Statistical analysis was performed using SPSS18.0software.ResultsOur research observed101patients,90of them are eligible subjects,11of them did not enter the clinical study or quit the research. Our subjects included outpatient and inpatient, age45-55years old. All of them were female, their course of disease last for1month to2years, in which the treatment group of45patients, with an average age of50.04±2.67; average duration of13.36±7.47months.The treatment group had45cases, at average of50.04±2.67years old, Their average duration is13.36±7.47months, Pittsburgh sleep quality index score of14.13±2.63points. While the control group had45cases, at average of50.42±2.96years old, Their average duration is13.51±7.76months, Pittsburgh sleep quality index score of14.14±2.60points.Comparable analysis of baseline characteristics of patients shows that two groups of baseline characteristics have comparability.After the treatment, We compared the scores. The efficiency of treatment group is93.33%while the control group is86.67%, with statistical significant difference (P<0.05). We compared every factor and total score of PSQI, Jin three needle therapy score better in improving sleeping quality, sleeping latency, and reducing sleep disorders and daytime dysfunction than the control group (P<0.05). But in other factors they have no statistical difference (P>0.05). Jin three needle therapy scores similar to the control group in total score of PSQI in one week (P>0.05), but scores better after4weeks treatment (P<0.05).According to the score of Hamilton’s depression scale(HAMD) Jin three needle therapy is better than the control group in improving depressive state and improving mood (P<0.05)In the safety detection, patients in both two groups did not occurred serious adverse reaction, which suggests two methods are both safe and reliable.According to above clinical research, it was preliminary proved that Jin three needle therapy is not only effective in the treatment for Menopausal insomnia, and can improve the degree of depression, at the same time, safe and reliable.ConelusionUse Jin three needle therapy to treat menopausal transition insomnia has definite clinical effect. Jin three needle therapy was significantly better than the control group in improving sleep quality, sleep efficiency, reducing the sleep disorders and daytime dysfunction. In the aspect of Short term efficacy (1week), Jin three needle therapy was similar to the control group, but in the aspect of long term efficacy (4weeks), its curative effect was significantly better. Moreover, Jin three needle therapy was better in improving the degree of depression and anxiety. Furthermore, it has less side effects and does not produce drug dependence, which is safe and reliable that worth clinical promotion.