Font Size: a A A

Study Of System Evaluation And Meta Analysis Of Effectiveness Of Detoxicate-blood Type Prescription In The Treatment Of Chronic Pelvic Inflammatory Disease

Posted on:2014-01-24Degree:DoctorType:Dissertation
Country:ChinaCandidate:F R WuFull Text:PDF
GTID:1224330398463264Subject:Gynecology of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
ObjectiveTraditional Chinese medicine can not only effectively alleviate the chronic pelvic inflammation in patients with symptoms, signs, and side effects. This study adopts the method of literature metrology, overall effective extraction of traditional Chinese medicine intervention in chronic pelvic inflammatory disease clinical research literature, the highest level design scheme of therapeutic research-a randomized controlled study for statistical objects, information extract formulas, scientific summary of the literature formula and drug use frequency, to reveal the use of the formulas. Then use of evidence-based medicine system evaluation and Meta analysis of research methods, sargentgloryvine stem soup, bolus of cassia twig tuckahoe, lower abdomen represented by stasis soup prescriptions, discuss blood detoxification class prescriptions for the treatment of chronic pelvic inflammatory disease of clinical curative effect, for future blood detoxification treatment of evidence-based evaluation provides a demonstration study.MethodsDesign scientific and effective information retrieval strategy, comprehensive database to retrieve large domestic Chinese, with Chinese hownet (CNKI), a Chinese biomedical literature database (CBM), chongqing weipu database (VIP), ten thousand medical digital and electronic databases (WF), such as journals, retrieve until June of2012. Collect intervention of chronic pelvic inflammatory disease, randomized controlled trial of traditional Chinese medicine research literature. Adopts the document manager Noteexpress2.0original document routing control, Excell2003is adopted to establish the literature information extraction table. System using literature metrology method, the effective extraction of traditional Chinese medicine intervention in chronic pelvic inflammatory disease clinical research literature of formulas, using scientific summary of the high frequency word types, dosage form, constitute Chinese medicine prescriptions and prescriptions of TCM prescriptions, late for evidence-based medicine evaluation basis for study and analysis.Using evidence-based medicine system evaluation and Meta analysis of research methods, selection of detoxicating blood for the treatment of high frequency of use of prescription, have red vine soup, bolus of cassia twig tuckahoe, lower abdomen by stasis soup for represent, respectively, from a large database of Chinese domestic collect randomized controlled trials, to retrieve as of December2012.5.0according to the Cochrane Review faced for quality assessment of the evidence-based medicine. Statistical analysis using RevMan5.0.20software. Respectively discussed on the basis of these prescriptions of traditional Chinese medicine treatment of chronic pelvic inflammatory disease of the clinical effectiveness, and its comparison with the conventional western medicine curative effect difference.ResultsSargentgloryvine stem soup based party evaluation system for treating chronic pelvic inflammatory disease/Meta analysis showed:sargentgloryvine stem compared with the total effective rate of western medicine soup RR=1.30,95%CI (1.19,1.19), P<0.00001, there is statistical significance; Sargentgloryvine stem soup with the total effective rate of western medicine RR=1.20,95%CI (1.13,1.13), P<0.00001, there is statistical significance; Sargentgloryvine stem soup compared with western medicine cure rate RR=2.69,95%CI (2.10,2.10), P<0.00001, there is statistical significance; Sargentgloryvine stem soup with western medicine cure rate RR=1.61,95%CI (1.41,1.41), P<0.00001, there is statistical significance; Sargentgloryvine stem soup decoction of the clinical symptom integrals compared with western medicine of WMD=2.53, ci (3.91,1.14), P<0.00001, with statistical significance.On the basis of cassia twig tuckahoe pills side systematic review of the treatment of chronic pelvic inflammatory disease/Meta analysis showed:cassia twig tuckahoe pills against western medicine clinical total effective rate RR=1.28,95%CI (1.18,1.18), P<0.00001, there is statistical significance; Bolus of cassia twig tuckahoe compared with western medicine clinical cure rate compare RR=1.95,95%CI(1.1.53,2.48), P<0.00001, there is statistical significance; Bolus of cassia twig tuckahoe cooperate with western medicine compared with western medicine clinical total effective rate RR=1.35,95%CI (1.16,1.16), P=0.0002, the difference was statistically significant; Bolus of cassia twig tuckahoe cooperate with western medicine compared with western medicine clinical cure rate RR=1.90,95%CI (1.52,1.52), P<0.00001, with statistical significance.ConclusionSoup of sargentgloryvine stem compared with western medicine in the aspect of improve the total effective rate, cure rate is superior to western medicine; Sargentgloryvine stem soup together with the western medicine compared with western medicine in improving total effective rate and cure rate were superior to western medicine; Soup of sargentgloryvine stem compared with western medicine is superior to western medicine in terms of improved clinical symptom scores. Bolus of cassia twig tuckahoe capsule)(compared with western medicine, cassia twig tuckahoe pills (capsule), compared with western medicine, western medicine treatment of chronic pelvic inflammatory disease, clinical cure rate and clinical total effective rate in improving patients, all have advantage. But because of literature quality is low, so need more high-quality randomized double-blind controlled trial to confirm the curative effect of treating chronic pelvic inflammatory disease.
Keywords/Search Tags:Traditional Chinese medicine, Chronic pelvic inflammation, Datamining, Clinical research literature
PDF Full Text Request
Related items