Effect Of Traditional Chinese Medicine On Inhibiting Inflammatory Reaction Of Chronic Obstructive Pulmonary Disease Based On Modern Literature

Objective:To analysis the effect of traditional Chinese medicine inhibiting the inflammatory reaction in COPD based on modern literature. To induce mediators of inflammation and Chinese Traditional medicine. To analyse correlation between medicine and inflammatory index.Methods:The study uses the method of computer retrieval. The retrieve sources are from Chinese National Knowledge Infrastructure (CNKI), Wan Fang, VIP database and with time limit from 2005 January to 2014 December. The search requirement is "key words=traditional Chinese medicine"or"COPD"or"inflammation mediators of COPD". Building a Excel table to record author, title, the time of publication, literature sources,COPD in acute stage and remission, TCM syndrome type, traditional Chinese medicine, changes of inflammatory mediators. To organize the literature. Selection of first five frequency inflammation mediators. Analyse pulmonary function,inflammatory mediators,symptom scores before and after treatment of these literatures. Count the frequency of traditional Chinese medicine,TCM syndrome with SPSS17.0 for statistical. Analyze and summarize the commonly used prescription, Chinese medicine and categories of TCM which affect inflammatory mediators.Results:170 articles were retrieved.49 articles met the inclusion criteria. Inflammation mediators of the top five were:TNF-α(18), IL-8 (14), CRP (9), IL-4 (8), IFN-γ(7). Contains five inflammatory markers in 34 literatures. In these literatures,the inflammatory mediators improved in statistical significance,compared with the traditional Chinese medicine group before and after treatment. The treatment groups compared with the control groups improved significantly,with statistically significant differences. Commonly used Chinese Pescriptions are the small Qinglong Decoction, Qianjin Weijing decoction, Qibai Pingfei capsule,Taohe Chengqi Decoction,Chuankezhi injection, Danhong injection. Commonly used drugs are licorice,astragalus,Salvia miltiorrhiza,pinellia tuber,scutellaria root,ginseng,schisandra fruit, bitter almond,mulberry,peach kernel. Commonly used efficiency of TCM are Buxu drug, Huatan zhike pingchuan drug, Huoxue huayu drug etc. In the improvement of TNF-α, IL-8, CRP mainly are Huatan zhike pingchuan drug,Buxu drug,Qingre drug. In the improvement of IL-4,IFN-γmainly are Buxu drug.Conclusion:This paper through the research of the modern literatures in the treatment of COPD with traditional Chinese medicine and to observe the inflammatory mediators,found that Chinese medicine could inhibit the inflammatory reaction of patients with COPD by adjusting the level of...